FOG02070
EOG87WM5W

sce:DGK1

Genes: 37

SGD Description
Diacylglycerol kinase; localized to the endoplasmic reticulum (ER); overproduction induces enlargement of ER-like membrane structures and suppresses a temperature-sensitive sly1 mutation; contains a CTP transferase domain


PomBase Description
phosphatidate cytidylyltransferase Ptp4 (predicted)


AspGD Description
Ortholog(s) have diacylglycerol kinase activity, role in phosphatidic acid biosynthetic process and integral component of endoplasmic reticulum membrane localization


References

Rieger KJ, et al. (1999 Jul). Chemotyping of yeast mutants using robotics.

Kosodo Y, et al. (2001 Aug). Multicopy suppressors of the sly1 temperature-sensitive mutation in the ER-Golgi vesicular transport in Saccharomyces cerevisiae.

Kim M, et al. (2002 Mar 19). A potential membrane protein involved in pre-tRNA splicing of Schizosaccharomyces pombe.

Kim H, et al. (2006 Jul 25). A global topology map of the Saccharomyces cerevisiae membrane proteome.

Han GS, et al. (2008 Jul 18). An unconventional diacylglycerol kinase that regulates phospholipid synthesis and nuclear membrane growth.

Han GS, et al. (2008 Jul 18). Characterization of the yeast DGK1-encoded CTP-dependent diacylglycerol kinase.

Beltrao P, et al. (2009 Jun 16). Evolution of phosphoregulation: comparison of phosphorylation patterns across yeast species.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 37 genes with posterior transmembrane prediction > 50%