FOG02064
EOG898SG9

sce:DGA1

Genes: 33

SGD Description
Diacylglycerol acyltransferase; catalyzes the terminal step of triacylglycerol (TAG) formation, acylates diacylglycerol using acyl-CoA as an acyl donor; Lro1p and Dga1p can O-acylate ceramides; localized to lipid particles


PomBase Description
diacylglycerol O-acyltransferase Dga1


AspGD Description
1-acylglycerol-3-phosphate acyltransferase


References

Cox KH, et al. (1999 Jun 15). Genome-wide transcriptional analysis in S. cerevisiae by mini-array membrane hybridization.

Sandager L, et al. (2002 Feb 22). Storage lipid synthesis is non-essential in yeast.

Sorger D, et al. (2002 Jan). Synthesis of triacylglycerols by the acyl-coenzyme A:diacyl-glycerol acyltransferase Dga1p in lipid particles of the yeast Saccharomyces cerevisiae.

Oelkers P, et al. (2002 Mar 15). The DGA1 gene determines a second triglyceride synthetic pathway in yeast.

Sorger D, et al. (2004 Jul 23). A yeast strain lacking lipid particles bears a defect in ergosterol formation.

Ferreira T, et al. (2004 Mar 15). Lipid dynamics in yeast under haem-induced unsaturated fatty acid and/or sterol depletion.

Heier C, et al. (2010 Sep). Identification of Yju3p as functional orthologue of mammalian monoglyceride lipase in the yeast Saccharomycescerevisiae.

Liu Q, et al. (2011 Apr 15). Functional and topological analysis of yeast acyl-CoA:diacylglycerol acyltransferase 2, an endoplasmic reticulum enzyme essential for triacylglycerol biosynthesis.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 32 genes with posterior transmembrane prediction > 50%

FOG02065
EOG898SG9

sce:absent

Genes: 2

AspGD Description
Has domain(s) with predicted transferase activity, transferring acyl groups, transferase activity, transferring acyl groups other than amino-acyl groups activity and role in metabolic process|Putative diacylglycerol acyl transferase

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 2 genes with posterior transmembrane prediction > 50%