FOG01977
EOG81RNCB

sce:ERG25

Genes: 36

SGD Description
C-4 methyl sterol oxidase; catalyzes the first of three steps required to remove two C-4 methyl groups from an intermediate in ergosterol biosynthesis; mutants accumulate the sterol intermediate 4,4-dimethylzymosterol


PomBase Description
C-4 methylsterol oxidase Erg25 (predicted)


AspGD Description
Putative C-4 methyl sterol oxidase; induced by fenpropimorph


References

Bard M, et al. (1996 Jan 9). Cloning and characterization of ERG25, the Saccharomyces cerevisiae gene encoding C-4 sterol methyl oxidase.

Li L, et al. (1996 Jul 12). Characterization of yeast methyl sterol oxidase (ERG25) and identification of a human homologue.

Mo C, et al. (2002 Jul 23). Protein-protein interactions among C-4 demethylation enzymes involved in yeast sterol biosynthesis.

Hitchcock AL, et al. (2003 Oct 28). A subset of membrane-associated proteins is ubiquitinated in response to mutations in the endoplasmic reticulum degradation machinery.

Deutschbauer AM, et al. (2005 Dec). Quantitative trait loci mapped to single-nucleotide resolution in yeast.

Hughes AL, et al. (2005 Mar 25). SREBP pathway responds to sterols and functions as an oxygen sensor in fission yeast.

Natter K, et al. (2005 May). The spatial organization of lipid synthesis in the yeast Saccharomyces cerevisiae derived from large scale green fluorescent protein tagging and high resolution microscopy.

Mo C, et al. (2005 Sep). Erg28p is a key protein in the yeast sterol biosynthetic enzyme complex.

Todd BL, et al. (2006 Apr). Sterol regulatory element binding protein is a principal regulator of anaerobic gene expression in fission yeast.

Savoldi M, et al. (2008 Oct). Farnesol induces the transcriptional accumulation of the Aspergillus nidulans Apoptosis-Inducing Factor (AIF)-like mitochondrial oxidoreductase.

Lando D, et al. (2012). The S. pombe histone H2A dioxygenase Ofd2 regulates gene expression during hypoxia.

Starita LM, et al. (2012 Jan). Sites of ubiquitin attachment in Saccharomyces cerevisiae.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 36 genes with posterior transmembrane prediction > 50%

FOG01978
EOG81RNCB

sce:absent

Genes: 1

Parent
paralog:FOG01977

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 1 genes with posterior transmembrane prediction > 50%

FOG01979
EOG81RNCB

sce:absent

Genes: 13

Parent
paralog:FOG01977


References

Kennedy MA, et al. (2000 Mar). Cloning and sequencing of the Candida albicans C-4 sterol methyl oxidase gene (ERG25) and expression of an ERG25 conditional lethal mutation in Saccharomyces cerevisiae.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 13 genes with posterior transmembrane prediction > 50%