FOG01976
EOG84QRH5

sce:ERG24

Genes: 36

SGD Description
C-14 sterol reductase; acts in ergosterol biosynthesis; mutants accumulate the abnormal sterol ignosterol (ergosta-8,14 dienol), and are viable under anaerobic growth conditions but inviable on rich medium under aerobic conditions


PomBase Description
C-14 sterol reductase Erg24 (predicted)


AspGD Description
C14 sterol reductase; predicted role in ergosterol synthesis; expression repressed by tunicamycin and DTT; induced by fenpropimorph|Ortholog(s) have role in ergosterol biosynthetic process and endoplasmic reticulum localization


References

Lorenz RT, et al. (1992 Nov). Cloning, sequencing, and disruption of the gene encoding sterol C-14 reductase in Saccharomyces cerevisiae.

Lai MH, et al. (1994 Mar 11). The identification of a gene family in the Saccharomyces cerevisiae ergosterol biosynthesis pathway.

Kim H, et al. (2006 Jul 25). A global topology map of the Saccharomyces cerevisiae membrane proteome.

Malavazi I, et al. (2007 Oct). Transcriptome analysis of the Aspergillus nidulans AtmA (ATM, Ataxia-Telangiectasia mutated) null mutant.

Savoldi M, et al. (2008 Oct). Farnesol induces the transcriptional accumulation of the Aspergillus nidulans Apoptosis-Inducing Factor (AIF)-like mitochondrial oxidoreductase.

Van Damme P, et al. (2012 Jul 31). N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 36 genes with posterior transmembrane prediction > 50%