FOG01966
EOG86T1JM

sce:MET1

Genes: 34

SGD Description
S-adenosyl-L-methionine uroporphyrinogen III transmethylase; involved in the biosynthesis of siroheme, a prosthetic group used by sulfite reductase; required for sulfate assimilation and methionine biosynthesis


PomBase Description
uroporphyrin methyltransferase (predicted)


AspGD Description
Siroheme synthase; involved in siroheme biosythesis


References

Kohli J, et al. (1977 Nov). Genetic Mapping in SCHIZOSACCHAROMYCES POMBE by Mitotic and Meiotic Analysis and Induced Haploidization.

Hansen J, et al. (1997 Jan 13). Siroheme biosynthesis in Saccharomyces cerevisiae requires the products of both the MET1 and MET8 genes.

Raux E, et al. (1999 Mar 15). The role of Saccharomyces cerevisiae Met1p and Met8p in sirohaem and cobalamin biosynthesis.

Chen D, et al. (2003 Jan). Global transcriptional responses of fission yeast to environmental stress.

Kennedy PJ, et al. (2008 Nov). A genome-wide screen of genes involved in cadmium tolerance in Schizosaccharomyces pombe.

Stewart EV, et al. (2011 Apr 22). Yeast SREBP cleavage activation requires the Golgi Dsc E3 ligase complex.

Wendland J, et al. (2011 Dec). Genome evolution in the eremothecium clade of the Saccharomyces complex revealed by comparative genomics.

Guo L, et al. (2016 Oct 13). Global Fitness Profiling Identifies Arsenic and Cadmium Tolerance Mechanisms in Fission Yeast.

Lee J, et al. (2017 Feb 20). Chromatin remodeller Fun30^Fft3 induces nucleosome disassembly to facilitate RNA polymerase II elongation.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG01967
EOG86T1JM
EOG8FXPRM

sce:MET8

Genes: 32

SGD Description
Bifunctional dehydrogenase and ferrochelatase; involved in the biosynthesis of siroheme, a prosthetic group used by sulfite reductase; required for sulfate assimilation and methionine biosynthesis


PomBase Description
siroheme synthase Met8 (predicted)


AspGD Description
Protein involved in siroheme biosythesis


References

Cherest H, et al. (1990 Feb 11). Nucleotide sequence of the MET8 gene of Saccharomyces cerevisiae.

Raux E, et al. (1999 Mar 15). The role of Saccharomyces cerevisiae Met1p and Met8p in sirohaem and cobalamin biosynthesis.

Schubert HL, et al. (2002 May 1). The structure of Saccharomyces cerevisiae Met8p, a bifunctional dehydrogenase and ferrochelatase.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 3 genes with posterior transmembrane prediction > 50%