FOG01959
EOG889344

sce:HEM4

Genes: 33

SGD Description
Uroporphyrinogen III synthase; catalyzes the conversion of hydroxymethylbilane to uroporphyrinogen III, the fourth step in heme biosynthesis; deficiency in the human homolog can result in the disease congenital erythropoietic porphyria


PomBase Description
uroporphyrinogen-III synthase Ups1


AspGD Description
Uroporphyrinogen III synthase (UroIII synthase, UroIII cosynthase)


References

Langgut W, et al. (1986). Isolation of a nuclear yeast gene involved in the mitochondrial import of cytoplasmically synthesized precursor proteins.

Amillet JM, et al. (1995 Apr 30). Isolation of the gene HEM4 encoding uroporphyrinogen III synthase in Saccharomyces cerevisiae.

Chéret G, et al. (1996 Sep). DNA sequence analysis of the VPH1-SNF2 region on chromosome XV of Saccharomyces cerevisiae.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 2 genes with posterior transmembrane prediction > 50%