FOG01944
EOG8P2NKW

sce:COQ4

Genes: 34

SGD Description
Protein with a role in ubiquinone (Coenzyme Q) biosynthesis; possibly functioning in stabilization of Coq7p; located on the matrix face of the mitochondrial inner membrane; component of a mitochondrial ubiquinone-synthesizing complex


PomBase Description
ubiquinone biosynthesis protein Coq4 (predicted)


AspGD Description
Ortholog(s) have role in ubiquinone biosynthetic process and mitochondrial inner membrane localization


References

Belogrudov GI, et al. (2001 Aug 1). Yeast COQ4 encodes a mitochondrial protein required for coenzyme Q synthesis.

Gin P, et al. (2005 Jan 28). Genetic evidence for a multi-subunit complex in coenzyme Q biosynthesis in yeast and the role of the Coq1 hexaprenyl diphosphate synthase.

Marbois B, et al. (2005 May 27). Coq3 and Coq4 define a polypeptide complex in yeast mitochondria for the biosynthesis of coenzyme Q.

Tran UC, et al. (2006 Jun 16). Complementation of Saccharomyces cerevisiae coq7 mutants by mitochondrial targeting of the Escherichia coli UbiF polypeptide: two functions of yeast Coq7 polypeptide in coenzyme Q biosynthesis.

Hsieh EJ, et al. (2007 Jul 1). Saccharomyces cerevisiae Coq9 polypeptide is a subunit of the mitochondrial coenzyme Q biosynthetic complex.

Marbois B, et al. (2009 Jan). The yeast Coq4 polypeptide organizes a mitochondrial protein complex essential for coenzyme Q biosynthesis.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 17 genes with posterior transmembrane prediction > 50%