FOG01877
EOG81G1K6

sce:SEC59

Genes: 34

SGD Description
Dolichol kinase; catalyzes the terminal step in dolichyl monophosphate (Dol-P) biosynthesis; required for viability and for normal rates of lipid intermediate synthesis and protein N-glycosylation


PomBase Description
dolichol kinase Sec59 (predicted)


AspGD Description
Has domain(s) with predicted transferase activity, transferring phosphorus-containing groups activity and membrane localization


References

Bernstein M, et al. (1989 Mar). Sec59 encodes a membrane protein required for core glycosylation in Saccharomyces cerevisiae.

Heller L, et al. (1992 Aug 1). Saccharomyces cerevisiae sec59 cells are deficient in dolichol kinase activity.

Kim H, et al. (2006 Jul 25). A global topology map of the Saccharomyces cerevisiae membrane proteome.

Rhind N, et al. (2011 May 20). Comparative functional genomics of the fission yeasts.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 34 genes with posterior transmembrane prediction > 50%