FOG01875
EOG8KWHB5

sce:PSA1

Genes: 34

SGD Description
GDP-mannose pyrophosphorylase (mannose-1-phosphate guanyltransferase); synthesizes GDP-mannose from GTP and mannose-1-phosphate in cell wall biosynthesis; required for normal cell wall structure


PomBase Description
mannose-1-phosphate guanyltransferase Mpg1


AspGD Description
Mannose-1-phosphate guanylyltransferase


References

Benton BK, et al. (1996 Jan). Over-expression of S. cerevisiae G1 cyclins restores the viability of alg1 N-glycosylation mutants.

Hashimoto H, et al. (1997 Jun 27). Saccharomyces cerevisiae VIG9 encodes GDP-mannose pyrophosphorylase, which is essential for protein glycosylation.

Warit S, et al. (1998 Sep). Cloning and sequencing of the Candida albicans homologue of SRB1/PSA1/VIG9, the essential gene encoding GDP-mannose pyrophosphorylase in Saccharomyces cerevisiae.

Ohta A, et al. (2000 Jul 26). The VIG9 gene products from the human pathogenic fungi Candida albicans and Candida glabrata encode GDP-mannose pyrophosphorylase.

Yoda K, et al. (2000 Sep). Defect in cell wall integrity of the yeast saccharomyces cerevisiae caused by a mutation of the GDP-mannose pyrophosphorylase gene VIG9.

Uccelletti D, et al. (2005 May). Enhanced secretion of heterologous proteins in Kluyveromyces lactis by overexpression of the GDP-mannose pyrophosphorylase, KlPsa1p.

Donoso I, et al. (2005 Sep). Mpg1, a fission yeast protein required for proper septum structure, is involved in cell cycle progression through cell-size checkpoint.

Malavazi I, et al. (2007 Oct). Transcriptome analysis of the Aspergillus nidulans AtmA (ATM, Ataxia-Telangiectasia mutated) null mutant.

Snaith HA, et al. (2011 Jul 1). Characterization of Mug33 reveals complementary roles for actin cable-dependent transport and exocyst regulators in fission yeast exocytosis.

Muñoz-Centeno MC, et al. (2012 Aug). Mpg2 interacts and cooperates with Mpg1 to maintain yeast glycosylation.

Starita LM, et al. (2012 Jan). Sites of ubiquitin attachment in Saccharomyces cerevisiae.

Van Damme P, et al. (2012 Jul 31). N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Mathiassen SG, et al. (2015 Aug 21). A Two-step Protein Quality Control Pathway for a Misfolded DJ-1 Variant in Fission Yeast.

Beckley JR, et al. (2015 Dec). A Degenerate Cohort of Yeast Membrane Trafficking DUBs Mediates Cell Polarity and Survival.

Kilchert C, et al. (2015 Dec 22). Regulation of mRNA Levels by Decay-Promoting Introns that Recruit the Exosome Specificity Factor Mmi1.

Lee J, et al. (2017 Feb 20). Chromatin remodeller Fun30<sup>Fft3</sup> induces nucleosome disassembly to facilitate RNA polymerase II elongation.

Mitochondrial localization predictions
Predotar TargetP MitoProt
Raw data
Phobius transmembrane predictions
0 genes with posterior transmembrane prediction > 50%