FOG01870
EOG8M37SX

sce:RER2

Genes: 34

SGD Description
Cis-prenyltransferase involved in dolichol synthesis; major enzyme of polyprenol synthesis in both the endoplasmic reticulum (ER) and in lipid droplets; participates in ER protein sorting


PomBase Description
cis-prenyltransferase


AspGD Description
Protein with a predicted role in retention of ER membrane proteins; expression enhanced by maltose; expression induced by tunicamycin and DTT


References

Sato M, et al. (1999 Jan). The yeast RER2 gene, identified by endoplasmic reticulum protein localization mutations, encodes cis-prenyltransferase, a key enzyme in dolichol synthesis.

Sato M, et al. (2001 Jun). Yeast Saccharomyces cerevisiae has two cis-prenyltransferases with different properties and localizations. Implication for their distinct physiological roles in dolichol synthesis.

Poznański J, et al. (2007 Jun 5). Precise bacterial polyprenol length control fails in Saccharomyces cerevisiae.

Wendland J, et al. (2011 Dec). Genome evolution in the eremothecium clade of the Saccharomyces complex revealed by comparative genomics.

Park EJ, et al. (2014 Sep 2). Mutation of Nogo-B receptor, a subunit of cis-prenyltransferase, causes a congenital disorder of glycosylation.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 4 genes with posterior transmembrane prediction > 50%

FOG01871
EOG8M37SX

sce:SRT1

Genes: 25

SGD Description
Cis-prenyltransferase; involved in synthesis of long-chain dolichols (19-22 isoprene units; as opposed to Rer2p which synthesizes shorter-chain dolichols); localizes to lipid bodies; transcription is induced during stationary phase


References

Sato M, et al. (1999 Jan). The yeast RER2 gene, identified by endoplasmic reticulum protein localization mutations, encodes cis-prenyltransferase, a key enzyme in dolichol synthesis.

Sato M, et al. (2001 Jun). Yeast Saccharomyces cerevisiae has two cis-prenyltransferases with different properties and localizations. Implication for their distinct physiological roles in dolichol synthesis.

Poznański J, et al. (2007 Jun 5). Precise bacterial polyprenol length control fails in Saccharomyces cerevisiae.

Park EJ, et al. (2014 Sep 2). Mutation of Nogo-B receptor, a subunit of cis-prenyltransferase, causes a congenital disorder of glycosylation.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 10 genes with posterior transmembrane prediction > 50%