FOG01814
EOG88932M

sce:GSY1;GSY2

Genes: 35

SGD Description
Glycogen synthase; expression induced by glucose limitation, nitrogen starvation, environmental stress, and entry into stationary phase; GSY1 has a paralog, GSY2, that arose from the whole genome duplication; relocalizes from nucleus to cytoplasmic foci upon DNA replication stress|Glycogen synthase; expression induced by glucose limitation, nitrogen starvation, heat shock, and stationary phase; activity regulated by cAMP-dependent, Snf1p and Pho85p kinases as well as by the Gac1p-Glc7p phosphatase; GSY2 has a paralog, GSY1, that arose from the whole genome duplication; relocalizes from cytoplasm to plasma membrane upon DNA replication stress


AspGD Description
Ortholog(s) have glycogen (starch) synthase activity, role in glycogen biosynthetic process and mitochondrion localization


References

Farkas I, et al. (1990 Dec 5). Isolation of the GSY1 gene encoding yeast glycogen synthase and evidence for the existence of a second gene.

Carabaza A, et al. (1990 Jun 1). Purification, characterization and partial amino acid sequence of glycogen synthase from Saccharomyces cerevisiae.

Farkas I, et al. (1991 Aug 25). Two glycogen synthase isoforms in Saccharomyces cerevisiae are coded by distinct genes that are differentially controlled.

Huang D, et al. (1998 Jun). Cyclin partners determine Pho85 protein kinase substrate specificity in vitro and in vivo: control of glycogen biosynthesis by Pcl8 and Pcl10.

Wilson WA, et al. (1999 Oct). Substrate targeting of the yeast cyclin-dependent kinase Pho85p by the cyclin Pcl10p.

Muthuvijayan V, et al. (2004). In silico reconstruction of nutrient-sensing signal transduction pathways in Aspergillus nidulans.

Gruhler A, et al. (2005 Mar). Quantitative phosphoproteomics applied to the yeast pheromone signaling pathway.

Chi A, et al. (2007 Feb 13). Analysis of phosphorylation sites on proteins from Saccharomyces cerevisiae by electron transfer dissociation (ETD) mass spectrometry.

Malavazi I, et al. (2007 Oct). Transcriptome analysis of the Aspergillus nidulans AtmA (ATM, Ataxia-Telangiectasia mutated) null mutant.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 1 genes with posterior transmembrane prediction > 50%