FOG01797
EOG8S7H5V

sce:SCW10;SCW4

Genes: 31

SGD Description
Cell wall protein with similarity to glucanases; may play a role in conjugation during mating based on mutant phenotype and its regulation by Ste12p; SWC10 has a paralog, SCW4, that arose from the whole genome duplication|Cell wall protein with similarity to glucanases; scw4 scw10 double mutants exhibit defects in mating; SCW4 has a paralog, SCW10, that arose from the whole genome duplication


AspGD Description
Putative beta-glucanase; predicted role in carbohydrate metabolism


References

Torosantucci A, et al. (1993 Aug). Identification of a 65-kDa mannoprotein as a main target of human cell-mediated immune response to Candida albicans.

Bromuro C, et al. (1994 Dec). Differential release of an immunodominant 65 kDa mannoprotein antigen from yeast and mycelial forms of Candida albicans.

Gomez MJ, et al. (1996 Jul). Purification and biochemical characterization of a 65-kilodalton mannoprotein (MP65), a main target of anti-Candida cell-mediated immune responses in humans.

Cappellaro C, et al. (1998 Oct). New potential cell wall glucanases of Saccharomyces cerevisiae and their involvement in mating.

La Valle R, et al. (2000 Dec). Generation of a recombinant 65-kilodalton mannoprotein, a major antigen target of cell-mediated immune response to Candida albicans.

Nisini R, et al. (2001 Jun). Antigenic properties and processing requirements of 65-kilodalton mannoprotein, a major antigen target of anti-Candida human T-cell response, as disclosed by specific human T-cell clones.

de Groot PW, et al. (2004 Aug). Proteomic analysis of Candida albicans cell walls reveals covalently bound carbohydrate-active enzymes and adhesins.

Castillo L, et al. (2006 Feb). Genomic response programs of Candida albicans following protoplasting and regeneration.

Arancia S, et al. (2006 Oct). Use of 65 kDa mannoprotein gene primers in Real Time PCR identification of Candida albicans in biological samples.

Soloviev DA, et al. (2007 Feb 15). Identification of pH-regulated antigen 1 released from Candida albicans as the major ligand for leukocyte integrin alphaMbeta2.

Sandini S, et al. (2007 May). The 65 kDa mannoprotein gene of Candida albicans encodes a putative beta-glucanase adhesin required for hyphal morphogenesis and experimental pathogenicity.

Hiller E, et al. (2007 Nov). Candida albicans Sun41p, a putative glycosidase, is involved in morphogenesis, cell wall biogenesis, and biofilm formation.

Yin QY, et al. (2007 Sep). Mass spectrometric quantitation of covalently bound cell wall proteins in Saccharomyces cerevisiae.

Pietrella D, et al. (2008 Sep). A Candida albicans mannoprotein deprived of its mannan moiety is efficiently taken up and processed by human dendritic cells and induces T-cell activation without stimulating proinflammatory cytokine production.

Kung LA, et al. (2009). Global analysis of the glycoproteome in Saccharomyces cerevisiae reveals new roles for protein glycosylation in eukaryotes.

Pierce CG, et al. (2009 Mar). Effect of tunicamycin on Candida albicans biofilm formation and maintenance.

de Groot PW, et al. (2009 Mar). Comprehensive genomic analysis of cell wall genes in Aspergillus nidulans.

Sorgo AG, et al. (2011 Aug). Effects of fluconazole on the secretome, the wall proteome, and wall integrity of the clinical fungus Candida albicans.

Wendland J, et al. (2011 Dec). Genome evolution in the eremothecium clade of the Saccharomyces complex revealed by comparative genomics.

Mitochondrial localization predictions
Predotar TargetP MitoProt
Raw data
Phobius transmembrane predictions
0 genes with posterior transmembrane prediction > 50%


FOG01798
EOG8S7H5V

sce:absent

Genes: 16
 





 
Mitochondrial localization predictions
Predotar TargetP MitoProt
Raw data
Phobius transmembrane predictions
1 genes with posterior transmembrane prediction > 50%


FOG01799
EOG8S7H5V

sce:SCW11

Genes: 29

SGD Description
Cell wall protein with similarity to glucanases; may play a role in conjugation during mating based on its regulation by Ste12p


AspGD Description
Protein similar to cell wall glucanase Scw10p; expression repressed by tunicamycin and DTT


References

Cappellaro C, et al. (1998 Oct). New potential cell wall glucanases of Saccharomyces cerevisiae and their involvement in mating.

Mitochondrial localization predictions
Predotar TargetP MitoProt
Raw data
Phobius transmembrane predictions
0 genes with posterior transmembrane prediction > 50%


FOG01800
EOG8S7H5V

sce:absent

Genes: 1
 





 
Mitochondrial localization predictions
Predotar TargetP MitoProt
Raw data
Phobius transmembrane predictions
0 genes with posterior transmembrane prediction > 50%