FOG01792
EOG87WM4K
sce:EXG1;SPR1
Genes: 42
EOG87WM4K
sce:EXG1;SPR1
Genes: 42
Protein description
Major exo-1,3-beta-glucanase of the cell wall
SGD Description
Major exo-1,3-beta-glucanase of the cell wall; involved in cell wall beta-glucan assembly; exists as three differentially glycosylated isoenzymes; EXG1 has a paralog, SPR1, that arose from the whole genome duplication|Sporulation-specific exo-1,3-beta-glucanase; contributes to ascospore thermoresistance; SPR1 has a paralog, EXG1, that arose from the whole genome duplication
PomBase Description
glucan 1,6-beta-glucosidase Exg1|glucan glucosidase Exg2, unknown specificity
AspGD Description
Putative exo-beta-1,3-glucanase; secreted glycoprotein precursor|Putative glucan exo-1,3-beta-glucosidase
References
Ramírez M, et al. (1990 Sep 1). Two glycosylation patterns for a single protein (exoglucanase) in Saccharomyces cerevisiae.
Vazquez de Aldana CR, et al. (1991 Jan 15). Nucleotide sequence of the exo-1,3-beta-glucanase-encoding gene, EXG1, of the yeast Saccharomyces cerevisiae.
Luna-Arias JP, et al. (1991 Nov). The major exoglucanase from Candida albicans: a non-glycosylated secretory monomer related to its counterpart from Saccharomyces cerevisiae.
Chambers RS, et al. (1993 Feb). An exo-beta-(1,3)-glucanase of Candida albicans: purification of the enzyme and molecular cloning of the gene.
Muthukumar G, et al. (1993 Jan). The Saccharomyces cerevisiae SPR1 gene encodes a sporulation-specific exo-1,3-beta-glucanase which contributes to ascospore thermoresistance.
San Segundo P, et al. (1993 Jun). SSG1, a gene encoding a sporulation-specific 1,3-beta-glucanase in Saccharomyces cerevisiae.
Basco RD, et al. (1993 Mar). Reduced efficiency in the glycosylation of the first sequon of Saccharomyces cerevisiae exoglucanase leads to the synthesis and secretion of a new glycoform of the molecule.
Mackenzie LF, et al. (1997 Feb 7). Identification of Glu-330 as the catalytic nucleophile of Candida albicans exo-beta-(1,3)-glucanase.
Cappellaro C, et al. (1998 Oct). New potential cell wall glucanases of Saccharomyces cerevisiae and their involvement in mating.
Stubbs HJ, et al. (1999 Aug). Hydrolase and transferase activities of the beta-1,3-exoglucanase of Candida albicans.
Cutfield SM, et al. (1999 Dec 3). The structure of the exo-beta-(1,3)-glucanase from Candida albicans in native and bound forms: relationship between a pocket and groove in family 5 glycosyl hydrolases.
Esteban PF, et al. (1999 Jan 30). Cloning and characterization of 1,3-beta-glucanase-encoding genes from non-conventional yeasts.
Lee CM, et al. (2004 Feb). The serine/threonine protein phosphatase SIT4 modulates yeast-to-hypha morphogenesis and virulence in Candida albicans.
Taylor SC, et al. (2004 Feb). The ER protein folding sensor UDP-glucose glycoprotein-glucosyltransferase modifies substrates distant to local changes in glycoprotein conformation.
Bauer S, et al. (2006 Jul 25). Development and application of a suite of polysaccharide-degrading enzymes for analyzing plant cell walls.
Brown V, et al. (2006 Oct). A glucose sensor in Candida albicans.
Coutinho PM, et al. (2009 Mar). Post-genomic insights into the plant polysaccharide degradation potential of Aspergillus nidulans and comparison to Aspergillus niger and Aspergillus oryzae.
de Groot PW, et al. (2009 Mar). Comprehensive genomic analysis of cell wall genes in Aspergillus nidulans.
Deshpande GP, et al. (2009 May 1). Screening a genome-wide S. pombe deletion library identifies novel genes and pathways involved in genome stability maintenance.
Maddi A, et al. (2009 Oct). Trifluoromethanesulfonic acid-based proteomic analysis of cell wall and secreted proteins of the ascomycetous fungi Neurospora crassa and Candida albicans.
Sorgo AG, et al. (2010 Aug). Mass spectrometric analysis of the secretome of Candida albicans.
Cho SJ, et al. (2010 Jun). Possible Roles of LAMMER Kinase Lkh1 in Fission Yeast by Comparative Proteome Analysis.
Kelly J, et al. (2010 Jun). Proteomic analysis of proteins released from growth-arrested Candida albicans following exposure to caspofungin.
Li X, et al. (2010 Jun). The MAP kinase-activated protein kinase Rck2p regulates cellular responses to cell wall stresses, filamentation and virulence in the human fungal pathogen Candida albicans.
Hernáez ML, et al. (2010 May 7). Identification of Candida albicans exposed surface proteins in vivo by a rapid proteomic approach.
Dueñas-Santero E, et al. (2010 Nov). Characterization of glycoside hydrolase family 5 proteins in Schizosaccharomyces pombe.
Patrick WM, et al. (2010 Nov). Carbohydrate binding sites in Candida albicans exo-β-1,3-glucanase and the role of the Phe-Phe 'clamp' at the active site entrance.
Tsai PW, et al. (2011). Characterizing the role of cell-wall β-1,3-exoglucanase Xog1p in Candida albicans adhesion by the human antimicrobial peptide LL-37.
Sorgo AG, et al. (2011 Aug). Effects of fluconazole on the secretome, the wall proteome, and wall integrity of the clinical fungus Candida albicans.
Taff HT, et al. (2012). A Candida biofilm-induced pathway for matrix glucan delivery: implications for drug resistance.
Pan X, et al. (2012 Nov 23). Identification of novel genes involved in DNA damage response by screening a genome-wide Schizosaccharomyces pombe deletion library.
Heilmann CJ, et al. (2013 Feb). Surface stress induces a conserved cell wall stress response in the pathogenic fungus Candida albicans.
Röhm M, et al. (2013 Jan). A family of secreted pathogenesis-related proteins in Candida albicans.
Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).
Garg A, et al. (2015 Aug 18). A new transcription factor for mitosis: in Schizosaccharomyces pombe, the RFX transcription factor Sak1 works with forkhead factors to regulate mitotic expression.
Nakazawa N, et al. (2015 Jun). RNA pol II transcript abundance controls condensin accumulation at mitotically up-regulated and heat-shock-inducible genes in fission yeast.
Dudin O, et al. (2015 Mar 30). A formin-nucleated actin aster concentrates cell wall hydrolases for cell fusion in fission yeast.
Malecki M, et al. (2016 Nov 25). Functional and regulatory profiling of energy metabolism in fission yeast.
Dudin O, et al. (2017 Apr). A systematic screen for morphological abnormalities during fission yeast sexual reproduction identifies a mechanism of actin aster formation for cell fusion.
| Mitochondrial localization predictions | ||
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| Predotar | TargetP | MitoProt |
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| Phobius transmembrane predictions
9 genes with posterior transmembrane prediction > 50% |
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FOG01793
EOG87WM4K
sce:absent
Genes: 14
EOG87WM4K
sce:absent
Genes: 14
References
Newport G, et al. (2003 Jan 17). Inactivation of Kex2p diminishes the virulence of Candida albicans.
De Groot PW, et al. (2003 Jul 15). Genome-wide identification of fungal GPI proteins.
Castillo L, et al. (2006 Feb). Genomic response programs of Candida albicans following protoplasting and regeneration.
Cabezón V, et al. (2009 Oct). Analysis of Candida albicans plasma membrane proteome.
Tsai PW, et al. (2011). Characterizing the role of cell-wall β-1,3-exoglucanase Xog1p in Candida albicans adhesion by the human antimicrobial peptide LL-37.
Singh RP, et al. (2011 Jul 15). Cap2-HAP complex is a critical transcriptional regulator that has dual but contrasting roles in regulation of iron homeostasis in Candida albicans.
Röhm M, et al. (2013 Jan). A family of secreted pathogenesis-related proteins in Candida albicans.
| Mitochondrial localization predictions | ||
|---|---|---|
| Predotar | TargetP | MitoProt |
 |
 |
 |
| Raw data
|
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| Phobius transmembrane predictions
7 genes with posterior transmembrane prediction > 50% |
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FOG01794
EOG87WM4K
sce:absent
Genes: 10
EOG87WM4K
sce:absent
Genes: 10
| Mitochondrial localization predictions | ||
|---|---|---|
| Predotar | TargetP | MitoProt |
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 |
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| Raw data
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| Phobius transmembrane predictions
7 genes with posterior transmembrane prediction > 50% |
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FOG01795
EOG87WM4K
sce:EXG2
Genes: 4
EOG87WM4K
sce:EXG2
Genes: 4
SGD Description
Exo-1,3-beta-glucanase; involved in cell wall beta-glucan assembly; may be anchored to the plasma membrane via a glycosylphosphatidylinositol (GPI) anchor
References
Wendland J, et al. (2011 Dec). Genome evolution in the eremothecium clade of the Saccharomyces complex revealed by comparative genomics.
| Mitochondrial localization predictions | ||
|---|---|---|
| Predotar | TargetP | MitoProt |
 |
 |
 |
| Raw data
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| Phobius transmembrane predictions
4 genes with posterior transmembrane prediction > 50% |
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FOG01796
EOG87WM4K
sce:absent
Genes: 2
EOG87WM4K
sce:absent
Genes: 2
| Mitochondrial localization predictions | ||
|---|---|---|
| Predotar | TargetP | MitoProt |
 |
 |
 |
| Raw data
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| Phobius transmembrane predictions
1 genes with posterior transmembrane prediction > 50% |
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