FOG01685
EOG8M37SD

sce:MTD1

Genes: 34

SGD Description
NAD-dependent 5,10-methylenetetrahydrafolate dehydrogenase; plays a catalytic role in oxidation of cytoplasmic one-carbon units; expression is regulated by Bas1p and Bas2p, repressed by adenine, and may be induced by inositol and choline


PomBase Description
methylenetetrahydrofolate reductase Mtd1 (predicted)


AspGD Description
Methylenetetrahydrofolate dehydrogenase (NAD+)


References

Barlowe CK, et al. (1990 Jul 31). Isolation and characterization of a novel eukaryotic monofunctional NAD(+)-dependent 5,10-methylenetetrahydrofolate dehydrogenase.

West MG, et al. (1993 Jan 5). Cloning and characterization of the Saccharomyces cerevisiae gene encoding NAD-dependent 5,10-methylenetetrahydrofolate dehydrogenase.

Monzingo AF, et al. (2000 Jul). The X-ray structure of the NAD-dependent 5,10-methylenetetrahydrofolate dehydrogenase from Saccharomyces cerevisiae.

Kennedy PJ, et al. (2008 Nov). A genome-wide screen of genes involved in cadmium tolerance in Schizosaccharomyces pombe.

Stewart EV, et al. (2011 Apr 22). Yeast SREBP cleavage activation requires the Golgi Dsc E3 ligase complex.

Pan X, et al. (2012 Nov 23). Identification of novel genes involved in DNA damage response by screening a genome-wide Schizosaccharomyces pombe deletion library.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Sideri T, et al. (2014 Dec 1). Parallel profiling of fission yeast deletion mutants for proliferation and for lifespan during long-term quiescence.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 12 genes with posterior transmembrane prediction > 50%