FOG01650
EOG85B01W

sce:CAB5

Genes: 33

SGD Description
Subunit of the CoA-Synthesizing Protein Complex (CoA-SPC); subunits of this complex are: Cab2p, Cab3p, Cab4p, Cab5p, Sis2p and Vhs3p; probable dephospho-CoA kinase (DPCK) that catalyzes the last step in coenzyme A biosynthesis; null mutant lethality is complemented by E. coli coaE (encoding DPCK); detected in purified mitochondria in high-throughput studies; also localized to lipid droplets


PomBase Description
dephospho-CoA kinase (predicted)


AspGD Description
Ortholog(s) have role in coenzyme A biosynthetic process and CoA-synthesizing protein complex, endoplasmic reticulum, lipid particle, mitochondrion, nuclear envelope localization


References

Hazbun TR, et al. (2003 Dec). Assigning function to yeast proteins by integration of technologies.

Reinders J, et al. (2006 Jul). Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics.

Wilson-Grady JT, et al. (2008 Mar). Phosphoproteome analysis of fission yeast.

Olzhausen J, et al. (2009 Apr). Genetic analysis of coenzyme A biosynthesis in the yeast Saccharomyces cerevisiae: identification of a conditional mutation in the pantothenate kinase gene CAB1.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 29 genes with posterior transmembrane prediction > 50%