FOG01563
EOG84J13F

sce:URA5;URA10

Genes: 34

SGD Description
Major orotate phosphoribosyltransferase (OPRTase) isozyme; catalyzes the fifth enzymatic step in de novo biosynthesis of pyrimidines, converting orotate into orotidine-5'-phosphate; URA5 has a paralog, URA10, that arose from the whole genome duplication|Minor orotate phosphoribosyltransferase (OPRTase) isozyme; catalyzes the fifth enzymatic step in the de novo biosynthesis of pyrimidines, converting orotate into orotidine-5'-phosphate; URA10 has a paralog, URA5, that arose from the whole genome duplication


PomBase Description
orotate phosphoribosyltransferase Ura5


AspGD Description
Orotate phosphoribosyltransferase


References

Palmer LM, et al. (1975 Jun 19). Pyrimidine biosynthesis in Aspergillus nidulans: isolation and preliminary characterisation of auxotrophic mutants.

de Montigny J, et al. (1989 Feb). Structure and expression of the URA5 gene of Saccharomyces cerevisiae.

de Montigny J, et al. (1990 Feb). Cloning and sequencing of URA10, a second gene encoding orotate phosphoribosyl transferase in Saccharomyces cerevisiae.

Hohmann S, et al. (1994 Oct). The byp1-3 allele of the Saccharomyces cerevisiae GGS1/TPS1 gene and its multi-copy suppressor tRNA(GLN) (CAG): Ggs1/Tps1 protein levels restraining growth on fermentable sugars and trehalose accumulation.

Sánchez M, et al. (1995 Apr 30). Cloning and sequencing of the URA5 gene from the yeast Yarrowia lipolytica.

Clutterbuck AJ, et al. (1997 Jun). The validity of the Aspergillus nidulans linkage map.

Aleksenko A, et al. (1999 Aug). Structural and transcriptional analysis of the pyrABCN, pyrD and pyrF genes in Aspergillus nidulans and the evolutionary origin of fungal dihydroorotases.

Bai X, et al. (1999 Sep 30). The URA5 gene encoding orotate-phosphoribosyl transferase of the yeast Kluyveromyces lactis: cloning, sequencing and use as a selectable marker.

Shimizu M, et al. (2009 Jan). Proteomic analysis of Aspergillus nidulans cultured under hypoxic conditions.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 6 genes with posterior transmembrane prediction > 50%

FOG01564
EOG84J13F

sce:absent

Genes: 1

Protein description
Uncharacterized paralog


Parent
paralog:FOG01563

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%