FOG01373
EOG83BK55

sce:MET17

Genes: 32

SGD Description
O-acetyl homoserine-O-acetyl serine sulfhydrylase; required for Methionine and cysteine biosynthesis


PomBase Description
homocysteine synthase Met17


AspGD Description
O-acetylhomoserine (thiol)-lyase


References

Paszewski A, et al. (1973). Studies on beta-cystathionase and omicron-acetylhomoserine sulfhydrylase as the enzymes of alternative methionine biosynthetic pathways in Aspergillus nidulans.

Paszewski A, et al. (1975 Nov). Enzymatic lesions in methionine mutants of Aspergillus nidulans: role and regulation of an alternative pathway for cysteine and methionine synthesis.

Brzywczy J, et al. (1993). Comparative studies on O-acetylhomoserine sulfhydrylase: physiological role and characterization of the Aspergillus nidulans enzyme.

Clutterbuck AJ, et al. (1997 Jun). The validity of the Aspergillus nidulans linkage map.

Sieńko M, et al. (1998 Feb). Structure and regulation of cysD, the homocysteine synthase gene of Aspergillus nidulans.

Dessen P, et al. (2000 Feb 22). The PAUSE software for analysis of translational control over protein targeting: application to E. nidulans membrane proteins.

Natorff R, et al. (2003 Aug). The Aspergillus nidulans metR gene encodes a bZIP protein which activates transcription of sulphur metabolism genes.

Brzywczy J, et al. (2007 Jun). Multiple fungal enzymes possess cysteine synthase activity in vitro.

Brzywczy J, et al. (2011 Feb). Novel mutations reveal two important regions in Aspergillus nidulans transcriptional activator MetR.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%