FOG01359
EOG8573RM

sce:MET16

Genes: 32

SGD Description
3'-phosphoadenylsulfate reductase; reduces 3'-phosphoadenylyl sulfate to adenosine-3',5'-bisphosphate and free sulfite using reduced thioredoxin as cosubstrate, involved in sulfate assimilation and methionine metabolism


PomBase Description
phosphoadenosine phosphosulfate reductase


AspGD Description
PAPS reductase


References

Arst HN Jr, et al. (1968 Jul 20). Genetic analysis of the first steps of sulphate metabolism in Aspergillus nidulans.

Gravel RA, et al. (1970 Dec). Genetic and accumulation studies in sulfite-requiring mutants of Aspergillus nidulans.

Clutterbuck AJ, et al. (1973 Jun). Gene symbols in Aspergillus nidulans.

Thomas D, et al. (1990 Sep 15). Gene-enzyme relationship in the sulfate assimilation pathway of Saccharomyces cerevisiae. Study of the 3'-phosphoadenylylsulfate reductase structural gene.

Paszewski A, et al. (1994). Sulphur metabolism.

Borges-Walmsley MI, et al. (1995 May 20). Isolation and characterisation of genes for sulphate activation and reduction in Aspergillus nidulans: implications for evolution of an allosteric control region by gene duplication.

Clutterbuck AJ, et al. (1997 Jun). The validity of the Aspergillus nidulans linkage map.

Schierová M, et al. (2000 Oct). Sulfate assimilation in Aspergillus terreus: analysis of genes encoding ATP-sulfurylase and PAPS-reductase.

Fujita Y, et al. (2006 Feb). Homocysteine accumulation causes a defect in purine biosynthesis: further characterization of Schizosaccharomyces pombe methionine auxotrophs.

Ma Y, et al. (2007 Aug). Six new amino acid-auxotrophic markers for targeted gene integration and disruption in fission yeast.

Breakspear A, et al. (2007 Sep). Aspergillus nidulans conidiation genes dewA, fluG, and stuA are differentially regulated in early vegetative growth.

Zuin A, et al. (2008 Jul 30). Mitochondrial dysfunction increases oxidative stress and decreases chronological life span in fission yeast.

Kennedy PJ, et al. (2008 Nov). A genome-wide screen of genes involved in cadmium tolerance in Schizosaccharomyces pombe.

Takeda K, et al. (2011). Identification of genes affecting the toxicity of anti-cancer drug bortezomib by genome-wide screening in S. pombe.

Brzywczy J, et al. (2011 Feb). Novel mutations reveal two important regions in Aspergillus nidulans transcriptional activator MetR.

Henry TC, et al. (2011 Feb). Systematic screen of Schizosaccharomyces pombe deletion collection uncovers parallel evolution of the phosphate signal transduction pathway in yeasts.

Ren L, et al. (2011 Feb 28). Systematic two-hybrid and comparative proteomic analyses reveal novel yeast pre-mRNA splicing factors connected to Prp19.

García-Santamarina S, et al. (2013 Dec). Methionine sulphoxide reductases revisited: free methionine as a primary target of H₂O₂stress in auxotrophic fission yeast.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Guo L, et al. (2016 Oct 13). Global Fitness Profiling Identifies Arsenic and Cadmium Tolerance Mechanisms in Fission Yeast.

Lee J, et al. (2017 Feb 20). Chromatin remodeller Fun30^Fft3 induces nucleosome disassembly to facilitate RNA polymerase II elongation.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 7 genes with posterior transmembrane prediction > 50%