FOG01304
EOG89CNS7

sce:HIS6

Genes: 35

Protein description
HIS4


SGD Description
Enzyme that catalyzes the fourth step in the histidine pathway; Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; mutations cause histidine auxotrophy and sensitivity to Cu, Co, and Ni salts


PomBase Description
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino) methylideneamino]imidazole-4-carboxamide isomerase (predicted)


AspGD Description
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase


References

Fani R, et al. (1997 Sep 15). Paralogous histidine biosynthetic genes: evolutionary analysis of the Saccharomyces cerevisiae HIS6 and HIS7 genes.

Quevillon-Cheruel S, et al. (2006 Jun). Crystal structure of the yeast His6 enzyme suggests a reaction mechanism.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 1 genes with posterior transmembrane prediction > 50%

FOG01305
EOG89CNS7

sce:absent

Genes: 1

Protein description
HIS4.2


Parent
ohnolog:FOG01304

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%