FOG01137
EOG88PK25
AAT2
sce:AAT2

Genes: 38

Protein description
Cytosolic aspartate aminotransferase, catabolic, involved in nitrogen metabolism


Features
[c],[x]


SGD Description
Cytosolic aspartate aminotransferase involved in nitrogen metabolism; localizes to peroxisomes in oleate-grown cells


PomBase Description
aspartate aminotransferase (predicted)


AspGD Description
Aspartate transaminase; phenylalanine:alphaketoglutarate aminotransferase|Aspartate transaminase; phenylalanine:alphaketoglutarate aminotransferase|Aspartate transaminase; phenylalanine:alphaketoglutarate aminotransferase|Aspartate transaminase; phenylalanine:alphaketoglutarate aminotransferase


References

Yagi T, et al. (1982 Jul). Aspartate: 2-oxoglutarate aminotransferase from bakers' yeast: crystallization and characterization.

Cronin VB, et al. (1990 Apr). Amino acid sequences of aspartate aminotransferases: the cytosolic isoenzymes from yeast and from human liver.

Cronin VB, et al. (1991 Jul 15). The amino acid sequence of the aspartate aminotransferase from baker's yeast (Saccharomyces cerevisiae).

Verleur N, et al. (1997 Aug 1). Cytosolic aspartate aminotransferase encoded by the AAT2 gene is targeted to the peroxisomes in oleate-grown Saccharomyces cerevisiae.

Jeffery CJ, et al. (1998 Jun). Crystal structure of Saccharomyces cerevisiae cytosolic aspartate aminotransferase.

Chi A, et al. (2007 Feb 13). Analysis of phosphorylation sites on proteins from Saccharomyces cerevisiae by electron transfer dissociation (ETD) mass spectrometry.

Kim Y, et al. (2011 Nov). Autophagy induced by rapamycin and carbon-starvation have distinct proteome profiles in Aspergillus nidulans.

Freitas JS, et al. (2011 Sep). Transcription of the Hsp30, Hsp70, and Hsp90 heat shock protein genes is modulated by the PalA protein in response to acid pH-sensing in the fungus Aspergillus nidulans.

Etxebeste O, et al. (2012). GmcA is a putative glucose-methanol-choline oxidoreductase required for the induction of asexual development in Aspergillus nidulans.

Saykhedkar S, et al. (2012 Jul 26). A time course analysis of the extracellular proteome of Aspergillus nidulans growing on sorghum stover.

Van Damme P, et al. (2012 Jul 31). N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

Mitochondrial localization predictions
Predotar TargetP MitoProt
Raw data
Phobius transmembrane predictions
0 genes with posterior transmembrane prediction > 50%


FOG01138
EOG88PK25
AAT1
sce:AAT1

Genes: 30

Protein description
Mitochondrial aspartate aminotransferase, anabolic


Features
[m]


SGD Description
Mitochondrial aspartate aminotransferase; catalyzes the conversion of oxaloacetate to aspartate in aspartate and asparagine biosynthesis


PomBase Description
aspartate aminotransferase (predicted)


AspGD Description
Mitochondrial aspartate aminotransferase


References

Morin PJ, et al. (1992 Dec 29). AAT1, a gene encoding a mitochondrial aspartate aminotransferase in Saccharomyces cerevisiae.

Chéret G, et al. (1993 Nov). The DNA sequence analysis of the HAP4-LAP4 region on chromosome XI of Saccharomyces cerevisiae suggests the presence of a second aspartate aminotransferase gene in yeast.

Greenwell PW, et al. (1995 Sep 8). TEL1, a gene involved in controlling telomere length in S. cerevisiae, is homologous to the human ataxia telangiectasia gene.

Sanchez Y, et al. (1996 Jan 19). Regulation of RAD53 by the ATM-like kinases MEC1 and TEL1 in yeast cell cycle checkpoint pathways.

Mallory JC, et al. (2000 Dec 5). Protein kinase activity of Tel1p and Mec1p, two Saccharomyces cerevisiae proteins related to the human ATM protein kinase.

Myung K, et al. (2001 Feb 9). Suppression of spontaneous chromosomal rearrangements by S phase checkpoint functions in Saccharomyces cerevisiae.

Usui T, et al. (2001 Jun). A DNA damage response pathway controlled by Tel1 and the Mre11 complex.

Clerici M, et al. (2001 Nov 15). Hyperactivation of the yeast DNA damage checkpoint by TEL1 and DDC2 overexpression.

D'Amours D, et al. (2001 Sep 1). The yeast Xrs2 complex functions in S phase checkpoint regulation.

Rouse J, et al. (2002 Apr). Lcd1p recruits Mec1p to DNA lesions in vitro and in vivo.

Nakada D, et al. (2003 Aug 15). ATM-related Tel1 associates with double-strand breaks through an Xrs2-dependent mechanism.

Chen D, et al. (2003 Jan). Global transcriptional responses of fission yeast to environmental stress.

Redon C, et al. (2003 Jul). Yeast histone 2A serine 129 is essential for the efficient repair of checkpoint-blind DNA damage.

Sickmann A, et al. (2003 Nov 11). The proteome of Saccharomyces cerevisiae mitochondria.

Shroff R, et al. (2004 Oct 5). Distribution and dynamics of chromatin modification induced by a defined DNA double-strand break.

Lisby M, et al. (2004 Sep 17). Choreography of the DNA damage response: spatiotemporal relationships among checkpoint and repair proteins.

Chakhparonian M, et al. (2005 Nov). A mutation in yeast Tel1p that causes differential effects on the DNA damage checkpoint and telomere maintenance.

Flott S, et al. (2005 Oct 15). Slx4 becomes phosphorylated after DNA damage in a Mec1/Tel1-dependent manner and is required for repair of DNA alkylation damage.

Reinders J, et al. (2006 Jul). Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics.

Gerke J, et al. (2012 Jun). Fungal S-adenosylmethionine synthetase and the control of development and secondary metabolism in Aspergillus nidulans.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Mitochondrial localization predictions
Predotar TargetP MitoProt
Raw data
Phobius transmembrane predictions
0 genes with posterior transmembrane prediction > 50%


FOG01139
EOG88PK25

sce:absent

Genes: 1

Protein description
Uncharacterized paralog


Features
[c]


AspGD Description
Aspartate transaminase; phenylalanine:alphaketoglutarate aminotransferase

Mitochondrial localization predictions
Predotar TargetP MitoProt
Raw data
Phobius transmembrane predictions
0 genes with posterior transmembrane prediction > 50%


FOG01140
EOG89KD6Q

sce:absent

Genes: 7

Suggested Analysis
Check if xenolog present in wan

Mitochondrial localization predictions
Predotar TargetP MitoProt
Raw data
Phobius transmembrane predictions
0 genes with posterior transmembrane prediction > 50%