FOG00807
EOG8P8D4C

sce:VMA3

Genes: 33

Protein description
VATPase.V0.c


SGD Description
Proteolipid subunit c of the V0 domain of vacuolar H(+)-ATPase; dicyclohexylcarbodiimide binding subunit; required for vacuolar acidification and important for copper and iron metal ion homeostasis


PomBase Description
V-type ATPase V0 subunit c (proteolipid subunit)


AspGD Description
Putative H+-transporting ATPase lipid-binding protein


References

Nelson H, et al. (1989 Apr 10). The progenitor of ATP synthases was closely related to the current vacuolar H+-ATPase.

Noumi T, et al. (1991 Mar 1). Mutational analysis of yeast vacuolar H(+)-ATPase.

Iwaki T, et al. (2004 Mar). Characterization of Schizosaccharomyces pombe mutants defective in vacuolar acidification and protein sorting.

Iwaki T, et al. (2006 Aug). A survey of all 11 ABC transporters in fission yeast: two novel ABC transporters are required for red pigment accumulation in a Schizosaccharomyces pombe adenine biosynthetic mutant.

Kim H, et al. (2006 Jul 25). A global topology map of the Saccharomyces cerevisiae membrane proteome.

Stephan J, et al. (2013 Aug). Chemical genetic screen in fission yeast reveals roles for vacuolar acidification, mitochondrial fission, and cellular GMP levels in lifespan extension.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 33 genes with posterior transmembrane prediction > 50%

FOG00808
EOG8P8D4C

sce:VMA11

Genes: 33

Protein description
VATPase.V0.c


SGD Description
Vacuolar ATPase V0 domain subunit c'; involved in proton transport activity; hydrophobic integral membrane protein (proteolipid) containing four transmembrane segments; N and C termini are in the vacuolar lumen


PomBase Description
V-type ATPase V0 proteolipid subunit (predicted)


AspGD Description
Ortholog(s) have endoplasmic reticulum, fungal-type vacuole, integral component of membrane localization


References

Shih CK, et al. (1990 Jul). Expression of a proteolipid gene from a high-copy-number plasmid confers trifluoperazine resistance to Saccharomyces cerevisiae.

Umemoto N, et al. (1991 Dec 25). VMA11, a novel gene that encodes a putative proteolipid, is indispensable for expression of yeast vacuolar membrane H(+)-ATPase activity.

Hirata R, et al. (1997 Feb 21). VMA11 and VMA16 encode second and third proteolipid subunits of the Saccharomyces cerevisiae vacuolar membrane H+-ATPase.

Gachet Y, et al. (2005 Dec 1). btn1, the Schizosaccharomyces pombe homologue of the human Batten disease gene CLN3, regulates vacuole homeostasis.

Kim H, et al. (2006 Jul 25). A global topology map of the Saccharomyces cerevisiae membrane proteome.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 33 genes with posterior transmembrane prediction > 50%

FOG00809
EOG8P8D4C

sce:VMA16

Genes: 33

Protein description
VATPase.V0.c


SGD Description
Subunit c'' of the vacuolar ATPase; v-ATPase functions in acidification of the vacuole; one of three proteolipid subunits of the V0 domain


PomBase Description
V-type ATPase V0 subunit c'' (predicted)


AspGD Description
Ortholog(s) have endoplasmic reticulum, integral component of membrane localization


References

Apperson M, et al. (1990 Apr 30). A yeast protein, homologous to the proteolipid of the chromaffin granule proton-ATPase, is important for cell growth.

Hirata R, et al. (1997 Feb 21). VMA11 and VMA16 encode second and third proteolipid subunits of the Saccharomyces cerevisiae vacuolar membrane H+-ATPase.

Gachet Y, et al. (2005 Dec 1). btn1, the Schizosaccharomyces pombe homologue of the human Batten disease gene CLN3, regulates vacuole homeostasis.

Fedorova ND, et al. (2005 Dec 8). Comparative analysis of programmed cell death pathways in filamentous fungi.

Kim H, et al. (2006 Jul 25). A global topology map of the Saccharomyces cerevisiae membrane proteome.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 33 genes with posterior transmembrane prediction > 50%

FOG00810
EOG8P8D4C

sce:absent

Genes: 1

AspGD Description
Has domain(s) with predicted hydrogen ion transmembrane transporter activity and role in ATP hydrolysis coupled proton transport

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 1 genes with posterior transmembrane prediction > 50%