FOG00773
EOG8FN34T

sce:COX19

Genes: 30

Protein description
COX.assembly


SGD Description
Protein required for cytochrome c oxidase assembly; located in the cytosol and mitochondrial intermembrane space; putative copper metallochaperone that delivers copper to cytochrome c oxidase; contains twin cysteine-x9-cysteine motifs


PomBase Description
mitochondrial respiratory chain complex IV assembly protein Cox19 (predicted)


AspGD Description
Cytochrome c oxidase subunit


References

Nobrega MP, et al. (2002 Oct 25). Characterization of COX19, a widely distributed gene required for expression of mitochondrial cytochrome oxidase.

Zuin A, et al. (2008 Jul 30). Mitochondrial dysfunction increases oxidative stress and decreases chronological life span in fission yeast.

Rhind N, et al. (2011 May 20). Comparative functional genomics of the fission yeasts.

Sun LL, et al. (2013). Global analysis of fission yeast mating genes reveals new autophagy factors.

Tay Z, et al. (2013). Cellular robustness conferred by genetic crosstalk underlies resistance against chemotherapeutic drug doxorubicin in fission yeast.

Graml V, et al. (2014 Oct 27). A genomic Multiprocess survey of machineries that control and link cell shape, microtubule organization, and cell-cycle progression.

Mojardín L, et al. (2015). Chromosome segregation and organization are targets of 5'-Fluorouracil in eukaryotic cells.

Nguyen TT, et al. (2015 Feb 11). Fitness profiling links topoisomerase II regulation of centromeric integrity to doxorubicin resistance in fission yeast.

Nguyen TT, et al. (2016 Jan 21). Predicting chemotherapeutic drug combinations through gene network profiling.

Mitochondrial localization predictions
Predotar TargetP MitoProt
Raw data
Phobius transmembrane predictions
0 genes with posterior transmembrane prediction > 50%