FOG00746
EOG866T56

sce:RIP1

Genes: 32

SGD Description
Ubiquinol-cytochrome-c reductase; a Rieske iron-sulfur protein of the mitochondrial cytochrome bc1 complex; transfers electrons from ubiquinol to cytochrome c1 during respiration; during import, Rip1p is first imported into the mitochondrial matrix where it is processed, acquires its Fe-S cluster, and is folded, then is translocated into the inner membrane by the action of a homo-oligomer of Bcs1p, and finally is delivered by Bcs1p to Complex III for assembly


PomBase Description
ubiquinol-cytochrome-c reductase complex subunit 5


AspGD Description
Ubiquinol-cytochrome c reductase


References

Beckmann JD, et al. (1987 Jun 25). Isolation and characterization of the nuclear gene encoding the Rieske iron-sulfur protein (RIP1) from Saccharomyces cerevisiae.

Gatti DL, et al. (1989 Jan 20). Structure and function of the mitochondrial bc1 complex. A mutational analysis of the yeast Rieske iron-sulfur protein.

Beckmann JD, et al. (1989 Mar 5). Mutational analysis of the mitochondrial Rieske iron-sulfur protein of Saccharomyces cerevisiae. I. Construction of a RIP1 deletion strain and isolation of temperature-sensitive mutants.

Graham LA, et al. (1991 Nov 25). Mutational analysis of the mitochondrial Rieske iron-sulfur protein of Saccharomyces cerevisiae. III. Import, protease processing, and assembly into the cytochrome bc1 complex of iron-sulfur protein lacking the iron-sulfur cluster.

di Rago JP, et al. (1996 Jun 28). Heterologous complementation of a Rieske iron-sulfur protein-deficient Saccharomyces cerevisiae by the Rip1 gene of Schizosaccharomyces pombe.

Hunte C, et al. (2000 Jun 15). Structure at 2.3 A resolution of the cytochrome bc(1) complex from the yeast Saccharomyces cerevisiae co-crystallized with an antibody Fv fragment.

Lange C, et al. (2002 Mar 5). Crystal structure of the yeast cytochrome bc1 complex with its bound substrate cytochrome c.

Zuin A, et al. (2008 Jul 30). Mitochondrial dysfunction increases oxidative stress and decreases chronological life span in fission yeast.

Solmaz SR, et al. (2008 Jun 20). Structure of complex III with bound cytochrome c in reduced state and definition of a minimal core interface for electron transfer.

Oh YT, et al. (2010 Mar). Proteomic analysis of early phase of conidia germination in Aspergillus nidulans.

Ma Y, et al. (2011). Genome-wide screening for genes associated with FK506 sensitivity in fission yeast.

Pusztahelyi T, et al. (2011 Feb). Comparison of transcriptional and translational changes caused by long-term menadione exposure in Aspergillus nidulans.

Sun LL, et al. (2013). Global analysis of fission yeast mating genes reveals new autophagy factors.

Takuma K, et al. (2013). The fission yeast php2 mutant displays a lengthened chronological lifespan.

Zhang L, et al. (2013). Genome-wide screening for genes associated with valproic acid sensitivity in fission yeast.

Dudin O, et al. (2017 Apr). A systematic screen for morphological abnormalities during fission yeast sexual reproduction identifies a mechanism of actin aster formation for cell fusion.

Lee J, et al. (2017 Feb 20). Chromatin remodeller Fun30^Fft3 induces nucleosome disassembly to facilitate RNA polymerase II elongation.

Su Y, et al. (2017 Jan). Loss of ppr3, ppr4, ppr6, or ppr10 perturbs iron homeostasis and leads to apoptotic cell death in Schizosaccharomyces pombe.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 14 genes with posterior transmembrane prediction > 50%