FOG00641
EOG8GB5T1
SDH3
sce:SDH3

Genes: 31

Protein description
Subunit of succinate dehydrogenase and of TIM22 translocase


SGD Description
Subunit of succinate dehydrogenase and of TIM22 translocase; functions as cytochrome b subunit of succinate dehydrogenase, which couples oxidation of succinate to transfer of electrons to ubiquinone as part of the TCA cycle and the mitochondrial respiratory chain; also required for mitochondrial inner membrane protein import as part of the TIM22 complex; SDH3 has a paralog, SHH3, that arose from the whole genome duplication


PomBase Description
succinate dehydrogenase (ubiquinone) cytochrome b subunit (predicted)


AspGD Description
Succinate dehydrogenase (ubiquinone)


References

Daignan-Fornier B, et al. (1994 Jun 3). Structure and regulation of SDH3, the yeast gene encoding the cytochrome b560 subunit of respiratory complex II.

Abraham PR, et al. (1994 Mar). Characterization of the Saccharomyces cerevisiae nuclear gene CYB3 encoding a cytochrome b polypeptide of respiratory complex II.

Clutterbuck AJ, et al. (1997 Jun). The validity of the Aspergillus nidulans linkage map.

Oyedotun KS, et al. (1999 Aug 20). The Saccharomyces cerevisiae succinate-ubiquinone oxidoreductase. Identification of Sdh3p amino acid residues involved in ubiquinone binding.

Lemire BD, et al. (2002 Jan 17). The Saccharomyces cerevisiae mitochondrial succinate:ubiquinone oxidoreductase.

Oyedotun KS, et al. (2004 Mar 5). Identification of the heme axial ligands in the cytochrome b562 of the Saccharomyces cerevisiae succinate dehydrogenase.

Oyedotun KS, et al. (2004 Mar 5). The quaternary structure of the Saccharomyces cerevisiae succinate dehydrogenase. Homology modeling, cofactor docking, and molecular dynamics simulation studies.

Espeso EA, et al. (2005 Oct). Discrepancies between recombination frequencies and physical distances in Aspergillus nidulans: implications for gene identification.

Flipphi M, et al. (2009 Mar). Biodiversity and evolution of primary carbon metabolism in Aspergillus nidulans and other Aspergillus spp.

Masuo S, et al. (2010 Dec). Global gene expression analysis of Aspergillus nidulans reveals metabolic shift and transcription suppression under hypoxia.

Stewart EV, et al. (2011 Apr 22). Yeast SREBP cleavage activation requires the Golgi Dsc E3 ligase complex.

Freitas JS, et al. (2011 Sep). Transcription of the Hsp30, Hsp70, and Hsp90 heat shock protein genes is modulated by the PalA protein in response to acid pH-sensing in the fungus Aspergillus nidulans.

Malecki M, et al. (2016). Identifying genes required for respiratory growth of fission yeast.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 31 genes with posterior transmembrane prediction > 50%

FOG00642

SHH3
sce:SHH3

Genes: 1

Protein description
Putative mitochondrial inner membrane protein of unknown function


Parent
ohnolog:FOG00641


SGD Description
Putative mitochondrial inner membrane protein of unknown function; although similar to paralogous Sdh3p, Shh3p is not a stoichiometric subunit of either succinate dehydrogenase or of the TIM22 translocase; SHH3 has a paralog, SDH3, that arose from the whole genome duplication


References

Gebert N, et al. (2011 Dec 9). Dual function of Sdh3 in the respiratory chain and TIM22 protein translocase of the mitochondrial inner membrane.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 1 genes with posterior transmembrane prediction > 50%