FOG00606
EOG87SQWJ
LPD1
sce:LPD1

Genes: 34

Protein description
Dihydrolipoamide dehydrogenase; the lipoamide dehydrogenase component (E3) of the pyruvate dehydrogenase and 2-oxoglutarate dehydrogenase multi-enzyme complexes


SGD Description
Dihydrolipoamide dehydrogenase; the lipoamide dehydrogenase component (E3) of the pyruvate dehydrogenase and 2-oxoglutarate dehydrogenase multi-enzyme complexes; PDH complex is concentrated in spots within the mitochondrial matrix, often near the ERMES complex and near peroxisomes; LPD1 has a paralog, IRC15, that arose from the whole genome duplication


PomBase Description
dihydrolipoamide dehydrogenase Dld1


AspGD Description
Precursor of dihydrolipoamide dehydrogenase


References

Browning KS, et al. (1988 Mar). Nucleotide sequence for yeast dihydrolipoamide dehydrogenase.

Ross J, et al. (1988 May). The nucleotide sequence of the LPD1 gene encoding lipoamide dehydrogenase in Saccharomyces cerevisiae: comparison between eukaryotic and prokaryotic sequences for related enzymes and identification of potential upstream control sites.

Sinclair DA, et al. (1995 Aug). Genetics of the synthesis of serine from glycine and the utilization of glycine as sole nitrogen source by Saccharomyces cerevisiae.

Jang YJ, et al. (1997 Oct 11). Fission yeast dihydrolipoamide dehydrogenase gene is involved in G1/S cell cycle progression.

Toyoda T, et al. (1998 Apr). Crystal structure of eucaryotic E3, lipoamide dehydrogenase from yeast.

Tarumoto Y, et al. (2013 Jun 28). Receptor for activated C-kinase (RACK1) homolog Cpc2 facilitates the general amino acid control response through Gcn2 kinase in fission yeast.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Lee J, et al. (2017 Feb 20). Chromatin remodeller Fun30^Fft3 induces nucleosome disassembly to facilitate RNA polymerase II elongation.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG00607
EOG87SQWJ
IRC15
sce:IRC15

Genes: 1

Parent
ohnolog:FOG00606


SGD Description
Microtubule associated protein; regulates microtubule dynamics; required for accurate meiotic chromosome segregation; null mutant displays large budded cells due to delayed mitotic progression, increased levels of spontaneous Rad52 foci; IRC15 has a paralog, LPD1, that arose from the whole genome duplication

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%