FOG00582
EOG851C88
IRC21
sce:IRC21

Genes: 33

SGD Description
Putative protein of unknown function; may be involved in resistance to carboplatin and cisplatin; null mutant displays increase in spontaneous Rad52p foci; contains a lipid-binding domain and binds cardiolipin in a large-scale study


PomBase Description
NADPH-hemoprotein reductase (predicted)


AspGD Description
Has domain(s) with predicted heme binding activity


References

Lee W, et al. (2005 Aug). Genome-wide requirements for resistance to functionally distinct DNA-damaging agents.

Alvaro D, et al. (2007 Dec). Genome-wide analysis of Rad52 foci reveals diverse mechanisms impacting recombination.

Wilson-Grady JT, et al. (2008 Mar). Phosphoproteome analysis of fission yeast.

Beltrao P, et al. (2009 Jun 16). Evolution of phosphoregulation: comparison of phosphorylation patterns across yeast species.

Han TX, et al. (2010). Global fitness profiling of fission yeast deletion strains by barcode sequencing.

Lando D, et al. (2012). The S. pombe histone H2A dioxygenase Ofd2 regulates gene expression during hypoxia.

Pancaldi V, et al. (2012 Apr). Predicting the fission yeast protein interaction network.

Kawashima SA, et al. (2012 Jul 27). Analyzing fission yeast multidrug resistance mechanisms to develop a genetically tractable model system for chemical biology.

Sugiyama T, et al. (2013 Jul). Red5 and three nuclear pore components are essential for efficient suppression of specific mRNAs during vegetative growth of fission yeast.

Anver S, et al. (2014 Aug). Yeast X-chromosome-associated protein 5 (Xap5) functions with H2A.Z to suppress aberrant transcripts.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Chen JS, et al. (2016 Sep). Discovery of genes involved in mitosis, cell division, cell wall integrity and chromosome segregation through construction of Schizosaccharomyces pombe deletion strains.

Lee J, et al. (2017 Feb 20). Chromatin remodeller Fun30^Fft3 induces nucleosome disassembly to facilitate RNA polymerase II elongation.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG00583
EOG851C88
CYB2
sce:CYB2

Genes: 26

SGD Description
Cytochrome b2 (L-lactate cytochrome-c oxidoreductase); component of the mitochondrial intermembrane space, required for lactate utilization; expression is repressed by glucose and anaerobic conditions


References

Guiard B, et al. (1975 May 29). More similarity between bakers'yeast L-(+)-lactate dehydrogenase and liver microsomal cytochrome b5.

Guiard B, et al. (1976). Complete amino acid sequence of the heme-binding core in bakers' yeast cytochrome b2 (L-(+)-lactate dehydrogenase).

Ghrir R, et al. (1984 Feb 15). Primary structure of flavocytochrome b2 from baker's yeast. Purification by reverse-phase high-pressure liquid chromatography and sequencing of fragment alpha cyanogen bromide peptides.

Guiard B, et al. (1985 Dec 1). Structure, expression and regulation of a nuclear gene encoding a mitochondrial protein: the yeast L(+)-lactate cytochrome c oxidoreductase (cytochrome b2).

Lederer F, et al. (1985 Oct 15). Complete amino acid sequence of flavocytochrome b2 from baker's yeast.

Xia ZX, et al. (1990 Apr 20). Molecular structure of flavocytochrome b2 at 2.4 A resolution.

Grandier-Vazeille X, et al. (2001 Aug 21). Yeast mitochondrial dehydrogenases are associated in a supramolecular complex.

Cunane LM, et al. (2002 Apr 2). Crystallographic study of the recombinant flavin-binding domain of Baker's yeast flavocytochrome b(2): comparison with the intact wild-type enzyme.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 18 genes with posterior transmembrane prediction > 50%

FOG00584
EOG851C88

sce:absent

Genes: 11

 





 

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 7 genes with posterior transmembrane prediction > 50%

FOG00585
EOG851C88

sce:absent

Genes: 7

AspGD Description
Lactic acid dehydrogenase|Lactic acid dehydrogenase

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG00586
EOG851C88

sce:absent

Genes: 2

AspGD Description
Lactic acid dehydrogenase

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG00587
EOG851C88
YNR1
sce:absent

Genes: 12

Protein description
NAD(P)H nitrate reductase


AspGD Description
Nitrate reductase


References

COVE DJ, et al. (1963 Apr 20). Independently segregating genetic loci concerned with nitrate reductase activity in Aspergillus nidulans.

PATEMAN JA, et al. (1964 Jan 4). A COMMON CO-FACTOR FOR NITRATE REDUCTASE AND XANTHINE DEHYDROGENASE WHICH ALSO REGULATES THE SYNTHESIS OF NITRATE REDUCTASE.

Cove DJ, et al. (1965 Nov 22). Purification of nitrate reductase and cytochrome c reductase from Aspergillus nidulans.

Cove DJ, et al. (1966 Jan 11). The induction and repression of nitrate reductase in the fungus Aspergillus nidulans.

Pateman JA, et al. (1967 Jul). Genetic and biochemical studies of nitrate reduction in Aspergillus nidulans.

Cove DJ, et al. (1967 Sep). Kinetic studies of the induction of nitrate reductase and cytochrome c reductase in the fungus Aspergillus nidulans.

Pateman JA, et al. (1969 Dec). Regulation of synthesis of glutamate dehydrogenase and glutamine synthetase in micro-organisms.

Cove DJ, et al. (1969 Mar). Autoregulation of the synthesis of nitrate reductase in Aspergillus nidulans.

Hartley MJ, et al. (1969 Mar-Apr). Reversion of non-nitrate utilizing (nia D) mutants of Aspergillus nidulans.

Arst HN Jr, et al. (1970). Molybdate metabolism in Aspergillus nidulans. I. Mutations affecting nitrate reductase and-or xanthine dehydrogenase.

Downey RJ, et al. (1973). The multimeric nature of NADPH-nitrate reductase from Aspergillus nidulans.

Downey RJ, et al. (1973 Feb 5). The role of molybdenum in formation of the NADPH-nitrate reductase by Aspergillus nidulans.

Clutterbuck AJ, et al. (1973 Jun). Gene symbols in Aspergillus nidulans.

Hynes MJ, et al. (1973 Nov). The effect of lack of a carbon source on nitrate-reductase activity in Aspergillus nidulans.

Hankinson O, et al. (1974 Apr 25). Regulation of the pentose phosphate pathway in the fungus Aspergillus nidulans. The effect of growth with nitrate.

MacDonlad DW, et al. (1974 Aug 15). Studies on temperature-sensitive mutants affecting the assimilatory nitrate reductase of Aspergillus nidulans.

McDonald DW, et al. (1974 Jul 1). Properties of the assimilatory nitrate reductase from Aspergillus nidulans.

Davis RH, et al. (1975). Compartmentation and regulation of fungal metabolism: genetic approaches.

Dunn-Coleman NS, et al. (1975). The regulation of nitrate reductase in the fungus Aspergillus nidulans.

Ketchum PA, et al. (1975 Apr 7). In vitro restoration of nitrate reductase: investigation of Aspergillus nidulans and Neurospora crassa nitrate reductase mutants.

Cove DJ, et al. (1976 Apr). Cholorate toxicity in Aspergillus nidulans: the selection and characterisation of chlorate resistant mutants.

Garrett RH, et al. (1976 Dec 8). Formation of NADPH-nitrate reductase activity in vitro from Aspergillus nidulans niaD and cnx mutants.

Cove DJ, et al. (1976 Jul 23). Chlorate toxicity in Aspergillus nidulans. Studies of mutants altered in nitrate assimilation.

Dunn-Coleman NS, et al. (1977 Apr 29). In vivo and in vitro studies of nitrate reductase regulation in Asperillus nidulans.

Lewis NJ, et al. (1977 Jun 15). The genetic control of molybdoflavoproteins in Aspergillus nidulans. A xanthine dehydrogenase I half-molecule in cnx- mutant strains of Aspergillus nidulans.

Garrett RH, et al. (1978). Nitrate assimilation in fungi.

Cove DJ, et al. (1979 Aug). Genetic studies of nitrate assimilation in Aspergillus nidulans.

Tomsett AB, et al. (1979 Aug). Deletion mapping of the niiA niaD gene region of Aspergillus nidulans.

Arst HN Jr, et al. (1979 Jul 2). Do the tightly linked structural genes for nitrate and nitrite reductases in Aspergillus nidulans form an operon? Evidence from an insertional translocation which separates them.

Minagawa N, et al. (1982 Mar). Purification and characterization of the assimilatory NADPH-nitrate reductase of Aspergillus nidulans.

Downey R, et al. (1982 Oct 29). De novo formation of the niaD gene directed protomer in the NADPH-nitrate reductase of Aspergillus nidulans.

Steiner FX, et al. (1982 Sep 7). Isoelectric focusing and two-dimensional analysis of purified nitrate reductase from Aspergillus nidulans.

Martinelli SD, et al. (1983 Jan). Diagnosis of nonsense mutations in Aspergillus nidulans.

Brownlee AG, et al. (1983 Sep). Nitrate uptake in Aspergillus nidulans and involvement of the third gene of the nitrate assimilation gene cluster.

Downey R, et al. (1984). A convener role for the cnxH gene specified component in the NADPH-nitrate reductase fron Aspergillus nidulans.

Martinelli SD, et al. (1984 Jun). Evidence for a nonsense mutation at the niaD locus of Aspergillus nidulans.

Arst HN Jr, et al. (1984 Sep). Regulation of gene expression in Aspergillus nidulans.

Wiame JM, et al. (1985). Nitrogen catabolite repression in yeasts and filamentous fungi.

Downey RJ, et al. (1987). Monoclonal antibody probes for the niaD specified subunit in the NADPH-nitrate reductase from Aspergillus nidulans.

Downey RJ, et al. (1988 Jan). Distinction of cnxH cofactor gene-specified protomers with monoclonal antibodies to Aspergillus nitrate reductase.

Bratt R, et al. (1988 Jul). Every ribosomal suppressor mutation in Aspergillus nidulans has a unique and highly pleiotropic phenotype.

Campbell EI, et al. (1989 Jul). Improved transformation efficiency of Aspergillus niger using the homologous niaD gene for nitrate reductase.

Daboussi MJ, et al. (1989 Jun). Transformation of seven species of filamentous fungi using the nitrate reductase gene of Aspergillus nidulans.

Malardier L, et al. (1989 May 15). Cloning of the nitrate reductase gene (niaD) of Aspergillus nidulans and its use for transformation of Fusarium oxysporum.

Johnstone IL, et al. (1990 Jun 15). Isolation and characterisation of the crnA-niiA-niaD gene cluster for nitrate assimilation in Aspergillus nidulans.

Debets AJ, et al. (1990 May). Genetic analysis of Aspergillus niger: isolation of chlorate resistance mutants, their use in mitotic mapping and evidence for an eighth linkage group.

Horng JS, et al. (1990 Nov). Development of a homologous transformation system for Aspergillus parasiticus with the gene encoding nitrate reductase.

Downey RJ, et al. (1991). Nitrate reactive structural gene mutants of Aspergillus nidulans.

Daboussi MJ, et al. (1991 Dec 20). Heterologous expression of the Aspergillus nidulans regulatory gene nirA in Fusarium oxysporum.

Burger G, et al. (1991 Feb). Molecular cloning and functional characterization of the pathway-specific regulatory gene nirA, which controls nitrate assimilation in Aspergillus nidulans.

Unkles SE, et al. (1991 Jan 1). crnA encodes a nitrate transporter in Aspergillus nidulans.

Punt PJ, et al. (1991 Jul 31). A twin-reporter vector for simultaneous analysis of expression signals of divergently transcribed, contiguous genes in filamentous fungi.

Burger G, et al. (1991 Nov). nirA, the pathway-specific regulatory gene of nitrate assimilation in Aspergillus nidulans, encodes a putative GAL4-type zinc finger protein and contains four introns in highly conserved regions.

Lloyd AT, et al. (1991 Nov). Codon usage in Aspergillus nidulans.

Hawker KL, et al. (1992 Feb). Nitrate reductase and nitrite reductase transcript levels in various mutants of Aspergillus nidulans: confirmation of autogenous regulation.

Unkles SE, et al. (1992 Feb 15). The Aspergillus niger niaD gene encoding nitrate reductase: upstream nucleotide and amino acid sequence comparisons.

Marzluf GA, et al. (1993). Regulation of sulfur and nitrogen metabolism in filamentous fungi.

Kinghorn JR, et al. (1994). Inorganic nitrogen assimilation: molecular aspects.

Gems D, et al. (1994 Feb). An 'instant gene bank' method for gene cloning by mutant complementation.

Garde J, et al. (1995 Mar 24). Site-directed mutagenesis of nitrate reductase from Aspergillus nidulans. Identification of some essential and some nonessential amino acids among conserved residues.

Thijs H, et al. (1995 May 10). Polarity of meiotic gene conversion is 5' to 3' within the niaD gene of Aspergillus nidulans.

Punt PJ, et al. (1995 Oct). The intergenic region between the divergently transcribed niiA and niaD genes of Aspergillus nidulans contains multiple NirA binding sites which act bidirectionally.

Kitamoto N, et al. (1995 Sep). The nitrate reductase gene from a shoyu koji mold, Aspergillus oryzae KBN616.

Amutan M, et al. (1996 Apr). Identification and cloning of a mobile transposon from Aspergillus niger var. awamori.

Chang PK, et al. (1996 Jun). Characterization of the Aspergillus parasiticus niaD and niiA gene cluster.

Haas H, et al. (1996 Nov 11). Sequence analysis and expression of the Penicillium chrysogenum nitrate reductase encoding gene (niaD).

Zucchi TM, et al. (1996 Sep). RNA-mediated transformation in Aspergillus nidulans recovers gene functions lost by deletion or by point mutations.

Bird D, et al. (1997 Jun). Gene targeting is locus dependent in the filamentous fungus Aspergillus nidulans.

Clutterbuck AJ, et al. (1997 Jun). The validity of the Aspergillus nidulans linkage map.

Lamb HK, et al. (1997 Nov). Deletion of the N-terminal region of the AREA protein is correlated with a derepressed phenotype with respect to nitrogen metabolite repression.

Muro-Pastor MI, et al. (1999 Mar 15). The GATA factor AreA is essential for chromatin remodelling in a eukaryotic bidirectional promoter.

Chang PK, et al. (2000 Apr 25). Characterization of the Aspergillus parasiticus major nitrogen regulatory gene, areA.

Dessen P, et al. (2000 Feb 22). The PAUSE software for analysis of translational control over protein targeting: application to E. nidulans membrane proteins.

Ramón A, et al. (2000 Jan). Deletion of the unique gene encoding a typical histone H1 has no apparent phenotype in Aspergillus nidulans.

Hall N, et al. (2000 Jun). Structure-function analysis of NADPH:nitrate reductase from Aspergillus nidulans: analysis of altered pyridine nucleotide specificity in vivo.

Zadra I, et al. (2000 Nov). xylP promoter-based expression system and its use for antisense downregulation of the Penicillium chrysogenum nitrogen regulator NRE.

Sandhu SS, et al. (2001 Jul). Transformation system of Beauveria bassiana and Metarhizium anisopliae using nitrate reductase gene of Aspergillus nidulans.

Unkles SE, et al. (2001 Nov 15). Apparent genetic redundancy facilitates ecological plasticity for nitrate transport.

Narendja F, et al. (2002 Apr). Nitrate and the GATA factor AreA are necessary for in vivo binding of NirA, the pathway-specific transcriptional activator of Aspergillus nidulans.

Muro-Pastor MI, et al. (2004 Apr). A paradoxical mutant GATA factor.

Takasaki K, et al. (2004 Apr). Unusual transcription regulation of the niaD gene under anaerobic conditions supporting fungal ammonia fermentation.

Takasaki K, et al. (2004 Mar 26). Fungal ammonia fermentation, a novel metabolic mechanism that couples the dissimilatory and assimilatory pathways of both nitrate and ethanol. Role of acetyl CoA synthetase in anaerobic ATP synthesis.

Takahashi T, et al. (2004 Oct). Efficient gene disruption in the koji-mold Aspergillus sojae using a novel variation of the positive-negative method.

Caddick MX, et al. (2006 Oct). Opposing signals differentially regulate transcript stability in Aspergillus nidulans.

Lubertozzi D, et al. (2006 Oct). Marker and promoter effects on heterologous expression in Aspergillus nidulans.

Wang Y, et al. (2007). Evidence for post-translational regulation of NrtA, the Aspergillus nidulans high-affinity nitrate transporter.

Bernreiter A, et al. (2007 Feb). Nuclear export of the transcription factor NirA is a regulatory checkpoint for nitrate induction in Aspergillus nidulans.

Berger H, et al. (2008 Sep). Dissecting individual steps of nitrogen transcription factor cooperation in the Aspergillus nidulans nitrate cluster.

Navarrete K, et al. (2009). Molecular characterization of the niaD and pyrG genes from Penicillium camemberti, and their use as transformation markers.

Basheer A, et al. (2009 Apr). A library-based method to rapidly analyse chromatin accessibility at multiple genomic regions.

Takaya N, et al. (2009 Jan). Response to hypoxia, reduction of electron acceptors, and subsequent survival by filamentous fungi.

Hagiwara D, et al. (2009 Nov). Transcriptional profiling for Aspergillusnidulans HogA MAPK signaling pathway in response to fludioxonil and osmotic stress.

Schinko T, et al. (2010 Nov). Transcriptome analysis of nitrate assimilation in Aspergillus nidulans reveals connections to nitric oxide metabolism.

Meyer V, et al. (2011 Mar). Aspergillus as a multi-purpose cell factory: current status and perspectives.

Terabayashi Y, et al. (2012 Jan). Conserved and specific responses to hypoxia in Aspergillus oryzae and Aspergillus nidulans determined by comparative transcriptomics.

Sarkar A, et al. (2012 Jul 31). Differential expression of silent polyketide biosynthesis gene clusters in chemostat cultures of Aspergillus nidulans.

Szilágyi M, et al. (2013 Jan). Transcriptome changes initiated by carbon starvation in Aspergillus nidulans.

Schinko T, et al. (2013 May). Pseudo-constitutivity of nitrate-responsive genes in nitrate reductase mutants.

Krol K, et al. (2013 Sep). RrmA regulates the stability of specific transcripts in response to both nitrogen source and oxidative stress.

Scazzocchio C, et al. (2013 Sep-Oct). In praise of erroneous hypotheses.

Tudzynski B, et al. (2014). Nitrogen regulation of fungal secondary metabolism in fungi.

Marcos AT, et al. (2016 Jan). Nitric oxide synthesis by nitrate reductase is regulated during development in Aspergillus.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 2 genes with posterior transmembrane prediction > 50%

FOG00588
EOG851C88
CBR1
sce:CBR1

Genes: 33

SGD Description
Microsomal cytochrome b reductase; not essential for viability; also detected in mitochondria; mutation in conserved NADH binding domain of the human ortholog results in type I methemoglobinemia


PomBase Description
cytochrome b5 reductase Cbr1 (predicted)


AspGD Description
Ortholog(s) have endoplasmic reticulum, plasma membrane localization


References

Kubota S, et al. (1977 Jan). Studies on the microsomal electron-transport system of anaerobically grown yeast. IV. Purification and characterization of NADH-cytochrome b5 reductase.

Bertrand JC, et al. (1984 Jul-Aug). Influence of oxygen on the microsomal electron transport system in Saccharomyces cerevisiae.

Csukai M, et al. (1994 Jan 15). Isolation and complete sequence of CBR, a gene encoding a putative cytochrome b reductase in Saccharomyces cerevisiae.

Lamb DC, et al. (1999 Dec 3). Biodiversity of the P450 catalytic cycle: yeast cytochrome b5/NADH cytochrome b5 reductase complex efficiently drives the entire sterol 14-demethylation (CYP51) reaction.

Kellis M, et al. (2003 May 15). Sequencing and comparison of yeast species to identify genes and regulatory elements.

Zhang Z, et al. (2005). Mapping of transcription start sites in Saccharomyces cerevisiae using 5' SAGE.

Zahedi RP, et al. (2006 Mar). Proteomic analysis of the yeast mitochondrial outer membrane reveals accumulation of a subclass of preproteins.

Tiedje C, et al. (2007 Oct 15). Proteins involved in sterol synthesis interact with Ste20 and regulate cell polarity.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 27 genes with posterior transmembrane prediction > 50%

FOG00589
EOG851C88
MCR1
sce:MCR1

Genes: 32

SGD Description
Mitochondrial NADH-cytochrome b5 reductase; involved in ergosterol biosynthesis


AspGD Description
Cytochrome-b5 reductase


References

Hahne K, et al. (1994 Dec 2). Incomplete arrest in the outer membrane sorts NADH-cytochrome b5 reductase to two different submitochondrial compartments.

Haucke V, et al. (1997 Jul). Analysis of the sorting signals directing NADH-cytochrome b5 reductase to two locations within yeast mitochondria.

Martin H, et al. (1998 Dec 1). The yeast mitochondrial intermembrane space: purification and analysis of two distinct fractions.

Lee JS, et al. (2001 Jul 2). Mitochondrial NADH-cytochrome b(5) reductase plays a crucial role in the reduction of D-erythroascorbyl free radical in Saccharomyces cerevisiae.

Krantz M, et al. (2004 Dec). Anaerobicity prepares Saccharomyces cerevisiae cells for faster adaptation to osmotic shock.

Burri L, et al. (2006 Apr). Integral membrane proteins in the mitochondrial outer membrane of Saccharomyces cerevisiae.

Zahedi RP, et al. (2006 Mar). Proteomic analysis of the yeast mitochondrial outer membrane reveals accumulation of a subclass of preproteins.

Juneau K, et al. (2007 Jan 30). High-density yeast-tiling array reveals previously undiscovered introns and extensive regulation of meiotic splicing.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 15 genes with posterior transmembrane prediction > 50%

FOG00590
EOG851C88
PGA3
sce:PGA3

Genes: 22

SGD Description
Putative cytochrome b5 reductase, localized to the plasma membrane; may be involved in regulation of lifespan; required for maturation of Gas1p and Pho8p, proposed to be involved in protein trafficking; PGA3 has a paralog, AIM33, that arose from the whole genome duplication


References

Kim H, et al. (2006 Jul 25). A global topology map of the Saccharomyces cerevisiae membrane proteome.

Yu L, et al. (2006 Nov). A survey of essential gene function in the yeast cell division cycle.

Jiménez-Hidalgo M, et al. (2009 Apr). NQR1 controls lifespan by regulating the promotion of respiratory metabolism in yeast.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 21 genes with posterior transmembrane prediction > 50%

FOG00591
EOG851C88

sce:absent

Genes: 20

AspGD Description
Lactic acid dehydrogenase

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG00592
EOG851C88

sce:absent

Genes: 3

AspGD Description
Has domain(s) with predicted heme binding, oxidoreductase activity and role in oxidation-reduction process

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 3 genes with posterior transmembrane prediction > 50%

FOG00593
EOG851C88

sce:absent

Genes: 2

AspGD Description
Has domain(s) with predicted heme binding, oxidoreductase activity and role in oxidation-reduction process|Has domain(s) with predicted heme binding, oxidoreductase activity and role in oxidation-reduction process

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG00594
EOG851C88

sce:absent

Genes: 2

AspGD Description
Has domain(s) with predicted electron carrier activity, heme binding, metal ion binding, molybdenum ion binding, oxidoreductase activity and role in nitrate assimilation, oxidation-reduction process|Has domain(s) with predicted electron carrier activity, heme binding, metal ion binding, molybdenum ion binding, oxidoreductase activity and role in nitrate assimilation, oxidation-reduction process

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 1 genes with posterior transmembrane prediction > 50%

FOG00595
EOG851C88

sce:absent

Genes: 2

AspGD Description
Putative cytochrome-b5 reductase; expression repressed by tunicamycin and DTT

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 2 genes with posterior transmembrane prediction > 50%

FOG00596
EOG851C88
CYB5
sce:CYB5

Genes: 38

SGD Description
Cytochrome b5; involved in the sterol and lipid biosynthesis pathways; acts as an electron donor to support sterol C5-6 desaturation


PomBase Description
cytochrome b5 (predicted)


AspGD Description
Cytochrome b5


References

Truan G, et al. (1994 May 3). Cloning and characterization of a yeast cytochrome b5-encoding gene which suppresses ketoconazole hypersensitivity in a NADPH-P-450 reductase-deficient strain.

Tallada VA, et al. (2002 Sep 30). Genome-wide search of Schizosaccharomyces pombe genes causing overexpression-mediated cell cycle defects.

Ma Y, et al. (2011). Genome-wide screening for genes associated with FK506 sensitivity in fission yeast.

Stewart EV, et al. (2011 Apr 22). Yeast SREBP cleavage activation requires the Golgi Dsc E3 ligase complex.

Wendland J, et al. (2011 Dec). Genome evolution in the eremothecium clade of the Saccharomyces complex revealed by comparative genomics.

Zhang L, et al. (2013). Genome-wide screening for genes associated with valproic acid sensitivity in fission yeast.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Rallis C, et al. (2014 Feb 15). Systematic screen for mutants resistant to TORC1 inhibition in fission yeast reveals genes involved in cellular ageing and growth.

Graml V, et al. (2014 Oct 27). A genomic Multiprocess survey of machineries that control and link cell shape, microtubule organization, and cell-cycle progression.

Mojardín L, et al. (2015). Chromosome segregation and organization are targets of 5'-Fluorouracil in eukaryotic cells.

Beckley JR, et al. (2015 Dec). A Degenerate Cohort of Yeast Membrane Trafficking DUBs Mediates Cell Polarity and Survival.

Zhang X, et al. (2015 Oct 9). Characterization of Tamoxifen as an Antifungal Agent Using the Yeast Schizosaccharomyces Pombe Model Organism.

Lee J, et al. (2017 Feb 20). Chromatin remodeller Fun30^Fft3 induces nucleosome disassembly to facilitate RNA polymerase II elongation.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 34 genes with posterior transmembrane prediction > 50%

FOG00597
EOG851C88

sce:absent

Genes: 13

 





 

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 6 genes with posterior transmembrane prediction > 50%

FOG00598
EOG851C88

sce:absent

Genes: 2

 





 

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 2 genes with posterior transmembrane prediction > 50%

FOG00599
EOG851C88
AIM33
sce:AIM33

Genes: 6

SGD Description
Putative protein of unknown function, highly conserved across species; homolog of human CYB5R4; null mutant displays reduced frequency of mitochondrial genome loss; AIM33 has a paralog, PGA3, that arose from the whole genome duplication


PomBase Description
mitochondrial cytochrome c-heme linkage protein Cyc2 (predicted)


References

Kim H, et al. (2006 Jul 25). A global topology map of the Saccharomyces cerevisiae membrane proteome.

Hess DC, et al. (2009 Mar). Computationally driven, quantitative experiments discover genes required for mitochondrial biogenesis.

Takeda K, et al. (2010 Feb 23). Synergistic roles of the proteasome and autophagy for mitochondrial maintenance and chronological lifespan in fission yeast.

Lando D, et al. (2012). The S. pombe histone H2A dioxygenase Ofd2 regulates gene expression during hypoxia.

Wang J, et al. (2013 Sep 1). Epe1 recruits BET family bromodomain protein Bdf2 to establish heterochromatin boundaries.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Sideri T, et al. (2014 Dec 1). Parallel profiling of fission yeast deletion mutants for proliferation and for lifespan during long-term quiescence.

Malecki M, et al. (2016). Identifying genes required for respiratory growth of fission yeast.

Malecki M, et al. (2016 Nov 25). Functional and regulatory profiling of energy metabolism in fission yeast.

Lee J, et al. (2017 Feb 20). Chromatin remodeller Fun30^Fft3 induces nucleosome disassembly to facilitate RNA polymerase II elongation.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 4 genes with posterior transmembrane prediction > 50%