FOG00404
EOG8HQC0H
ACS1
sce:ACS1
Genes: 34
EOG8HQC0H
ACS1
sce:ACS1
Genes: 34
Protein description
Acetyl-coA synthetase isoform expressed with non-fermentable carbon sources. Spo gene expressed with fermentable carbon sources.
SGD Description
Acetyl-coA synthetase isoform; along with Acs2p, acetyl-coA synthetase isoform is the nuclear source of acetyl-coA for histone acetylation; expressed during growth on nonfermentable carbon sources and under aerobic conditions
PomBase Description
acetyl-CoA ligase (predicted)
AspGD Description
Putative acetyl-CoA synthase
References
Armitt S, et al. (1976 Feb). Analysis of acetate non-utilizing (acu) mutants in Aspergillus nidulans.
Payton M, et al. (1976 May). Agar as a carbon source and its effect on the utilization of other carbon sources by acetate non-utilizing (acu) mutants of Aspergillus nidulans.
Frenkel EP, et al. (1977 Jan 25). Purification and properties of acetyl coenzyme A synthetase from bakers' yeast.
Hynes MJ, et al. (1977 Sep). Induction of the acetamidase of Aspergillus nidulans by acetate metabolism.
Midelfort CF, et al. (1978 Oct 25). The stereochemical course of acetate activation by yeast acetyl-CoA synthetase.
Bal J, et al. (1979 Dec). Allele specific and locus non-specific suppressors in Aspergillus nidulans.
Kelly JM, et al. (1981 Apr). The regulation of phosphoenolpyruvate carboxykinase and the NADP-linked malic enzyme in Aspergillus nidulans.
Sandeman RA, et al. (1989 Jul). Isolation of the facA (acetyl-coenzyme A synthetase) and acuE (malate synthase) genes of Aspergillus nidulans.
Connerton IF, et al. (1990 Mar). Comparison and cross-species expression of the acetyl-CoA synthetase genes of the Ascomycete fungi, Aspergillus nidulans and Neurospora crassa.
Lloyd AT, et al. (1991 Nov). Codon usage in Aspergillus nidulans.
Sandeman RA, et al. (1991 Sep). Molecular organisation of the malate synthase genes of Aspergillus nidulans and Neurospora crassa.
Birch PR, et al. (1992). Nucleotide sequence of a gene from Phanerochaete chrysosporium that shows homology to the facA gene of Aspergillus nidulans.
Maconochie MK, et al. (1992 Aug). The acu-1 gene of Coprinus cinereus is a regulatory gene required for induction of acetate utilisation enzymes.
De Virgilio C, et al. (1992 Dec). Cloning and disruption of a gene required for growth on acetate but not on ethanol: the acetyl-coenzyme A synthetase gene of Saccharomyces cerevisiae.
Kujau M, et al. (1992 Mar). Characterization of mutants of the yeast Yarrowia lipolytica defective in acetyl-coenzyme A synthetase.
Saleeba JA, et al. (1992 Nov). Characterization of the amdA-regulated aciA gene of Aspergillus nidulans.
Steensma HY, et al. (1993 Apr). Genetic and physical localization of the acetyl-coenzyme A synthetase gene ACS1 on chromosome I of Saccharomyces cerevisiae.
MartÃnez-Blanco H, et al. (1993 Aug 25). Characterisation of the gene encoding acetyl-CoA synthetase in Penicillium chrysogenum: conservation of intron position in plectomycetes.
Gouka RJ, et al. (1993 Jan). Development of a new transformant selection system for Penicillium chrysogenum: isolation and characterization of the P. chrysogenum acetyl-coenzyme A synthetase gene (facA) and its use as a homologous selection marker.
Sealy-Lewis HM, et al. (1994 Jan). A new selection method for isolating mutants defective in acetate utilisation in Aspergillus nidulans.
Van den Berg MA, et al. (1995 Aug 1). ACS2, a Saccharomyces cerevisiae gene encoding acetyl-coenzyme A synthetase, essential for growth on glucose.
Kratzer S, et al. (1995 Aug 8). Carbon source-dependent regulation of the acetyl-coenzyme A synthetase-encoding gene ACS1 from Saccharomyces cerevisiae.
van den Berg MA, et al. (1996 Nov 15). The two acetyl-coenzyme A synthetases of Saccharomyces cerevisiae differ with respect to kinetic properties and transcriptional regulation.
de Jong-Gubbels P, et al. (1997 Aug 1). The Saccharomyces cerevisiae acetyl-coenzyme A synthetase encoded by the ACS1 gene, but not the ACS2-encoded enzyme, is subject to glucose catabolite inactivation.
Clutterbuck AJ, et al. (1997 Jun). The validity of the Aspergillus nidulans linkage map.
Todd RB, et al. (1998 Apr 1). FacB, the Aspergillus nidulans activator of acetate utilization genes, binds dissimilar DNA sequences.
Stemple CJ, et al. (1998 Dec). The facC gene of Aspergillus nidulans encodes an acetate-inducible carnitine acetyltransferase.
Papadopoulou S, et al. (1999 Sep 1). The Aspergillus niger acuA and acuB genes correspond to the facA and facB genes in Aspergillus nidulans.
Dessen P, et al. (2000 Feb 22). The PAUSE software for analysis of translational control over protein targeting: application to E. nidulans membrane proteins.
Brock M, et al. (2000 Mar). Methylcitrate synthase from Aspergillus nidulans: implications for propionate as an antifungal agent.
Jones IG, et al. (2001 Feb). ADHII in Aspergillus nidulans is induced by carbon starvation stress.
Lodi T, et al. (2001 Sep). Three target genes for the transcriptional activator Cat8p of Kluyveromyces lactis: acetyl coenzyme A synthetase genes KlACS1 and KlACS2 and lactate permease gene KlJEN1.
Hynes MJ, et al. (2002 Jan). Regulation of the acuF gene, encoding phosphoenolpyruvate carboxykinase in the filamentous fungus Aspergillus nidulans.
Kumar A, et al. (2002 Mar 15). Subcellular localization of the yeast proteome.
Flipphi M, et al. (2002 May 15). Characteristics of physiological inducers of the ethanol utilization (alc) pathway in Aspergillus nidulans.
Flipphi M, et al. (2003 Apr 4). Onset of carbon catabolite repression in Aspergillus nidulans. Parallel involvement of hexokinase and glucokinase in sugar signaling.
Zeeman AM, et al. (2003 Jan 15). The acetyl co-enzyme A synthetase genes of Kluyveromyces lactis.
Sickmann A, et al. (2003 Nov 11). The proteome of Saccharomyces cerevisiae mitochondria.
Flipphi M, et al. (2003 Sep). Relationships between the ethanol utilization (alc) pathway and unrelated catabolic pathways in Aspergillus nidulans.
Brock M, et al. (2004 Aug). On the mechanism of action of the antifungal agent propionate.
Sims AH, et al. (2004 Feb). Use of expressed sequence tag analysis and cDNA microarrays of the filamentous fungus Aspergillus nidulans.
Jogl G, et al. (2004 Feb 17). Crystal structure of yeast acetyl-coenzyme A synthetase in complex with AMP.
Takasaki K, et al. (2004 Mar 26). Fungal ammonia fermentation, a novel metabolic mechanism that couples the dissimilatory and assimilatory pathways of both nitrate and ethanol. Role of acetyl CoA synthetase in anaerobic ATP synthesis.
Zhang YQ, et al. (2004 Oct). Connection of propionyl-CoA metabolism to polyketide biosynthesis in Aspergillus nidulans.
David H, et al. (2006). Metabolic network driven analysis of genome-wide transcription data from Aspergillus nidulans.
Mogensen J, et al. (2006 Aug). Transcription analysis using high-density micro-arrays of Aspergillus nidulans wild-type and creA mutant during growth on glucose or ethanol.
Takahashi H, et al. (2006 Jul 21). Nucleocytosolic acetyl-coenzyme a synthetase is required for histone acetylation and global transcription.
Hynes MJ, et al. (2006 May). Regulatory genes controlling fatty acid catabolism and peroxisomal functions in the filamentous fungus Aspergillus nidulans.
Salazar M, et al. (2009 Dec). Uncovering transcriptional regulation of glycerol metabolism in Aspergilli through genome-wide gene expression data analysis.
Shimizu M, et al. (2009 Jan). Proteomic analysis of Aspergillus nidulans cultured under hypoxic conditions.
Flipphi M, et al. (2009 Mar). Biodiversity and evolution of primary carbon metabolism in Aspergillus nidulans and other Aspergillus spp.
Hynes MJ, et al. (2010 Jul). ATP-citrate lyase is required for production of cytosolic acetyl coenzyme A and development in Aspergillus nidulans.
Oh YT, et al. (2010 Mar). Proteomic analysis of early phase of conidia germination in Aspergillus nidulans.
Wendland J, et al. (2011 Dec). Genome evolution in the eremothecium clade of the Saccharomyces complex revealed by comparative genomics.
Saykhedkar S, et al. (2012 Jul 26). A time course analysis of the extracellular proteome of Aspergillus nidulans growing on sorghum stover.
Georgakopoulos P, et al. (2012 Nov). SAGA complex components and acetate repression in Aspergillus nidulans.
Nakamura T, et al. (2012 Sep). Impaired coenzyme A synthesis in fission yeast causes defective mitosis, quiescence-exit failure, histone hypoacetylation and fragile DNA.
Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).
Beckley JR, et al. (2015 Dec). A Degenerate Cohort of Yeast Membrane Trafficking DUBs Mediates Cell Polarity and Survival.
Malecki M, et al. (2016 Nov 25). Functional and regulatory profiling of energy metabolism in fission yeast.
| Mitochondrial localization predictions | ||
|---|---|---|
| Predotar | TargetP | MitoProt |
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| Raw data
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| Phobius transmembrane predictions
24 genes with posterior transmembrane prediction > 50% |
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FOG00405
EOG8HQC0H
ACS2
sce:ACS2
Genes: 26
EOG8HQC0H
ACS2
sce:ACS2
Genes: 26
Protein description
Acetyl-coA synthetase isoform expressed with fermentable carbon sources
Parent
paralog:FOG00404
SGD Description
Acetyl-coA synthetase isoform; along with Acs1p, acetyl-coA synthetase isoform is the nuclear source of acetyl-coA for histone acetylation; mutants affect global transcription; required for growth on glucose; expressed under anaerobic conditions
References
Frenkel EP, et al. (1977 Jan 25). Purification and properties of acetyl coenzyme A synthetase from bakers' yeast.
Midelfort CF, et al. (1978 Oct 25). The stereochemical course of acetate activation by yeast acetyl-CoA synthetase.
De Virgilio C, et al. (1992 Dec). Cloning and disruption of a gene required for growth on acetate but not on ethanol: the acetyl-coenzyme A synthetase gene of Saccharomyces cerevisiae.
Van den Berg MA, et al. (1995 Aug 1). ACS2, a Saccharomyces cerevisiae gene encoding acetyl-coenzyme A synthetase, essential for growth on glucose.
Kratzer S, et al. (1995 Aug 8). Carbon source-dependent regulation of the acetyl-coenzyme A synthetase-encoding gene ACS1 from Saccharomyces cerevisiae.
van den Berg MA, et al. (1996 Nov 15). The two acetyl-coenzyme A synthetases of Saccharomyces cerevisiae differ with respect to kinetic properties and transcriptional regulation.
de Jong-Gubbels P, et al. (1997 Aug 1). The Saccharomyces cerevisiae acetyl-coenzyme A synthetase encoded by the ACS1 gene, but not the ACS2-encoded enzyme, is subject to glucose catabolite inactivation.
Lodi T, et al. (2001 Sep). Three target genes for the transcriptional activator Cat8p of Kluyveromyces lactis: acetyl coenzyme A synthetase genes KlACS1 and KlACS2 and lactate permease gene KlJEN1.
Peng J, et al. (2003 Aug). A proteomics approach to understanding protein ubiquitination.
Zeeman AM, et al. (2003 Jan 15). The acetyl co-enzyme A synthetase genes of Kluyveromyces lactis.
Takahashi H, et al. (2006 Jul 21). Nucleocytosolic acetyl-coenzyme a synthetase is required for histone acetylation and global transcription.
| Mitochondrial localization predictions | ||
|---|---|---|
| Predotar | TargetP | MitoProt |
 |
 |
 |
| Raw data
|
||
| Phobius transmembrane predictions
16 genes with posterior transmembrane prediction > 50% |
||
FOG00406
EOG8HQC0H
ACS3
sce:absent
Genes: 3
EOG8HQC0H
ACS3
sce:absent
Genes: 3
Protein description
Uncharacterized acetyl-coA synthetase paralog
Parent
paralog:FOG00404
AspGD Description
Putative acetyl-CoA synthase
References
Zhang YQ, et al. (2004 Oct). Connection of propionyl-CoA metabolism to polyketide biosynthesis in Aspergillus nidulans.
Salazar M, et al. (2009 Dec). Uncovering transcriptional regulation of glycerol metabolism in Aspergilli through genome-wide gene expression data analysis.
Flipphi M, et al. (2009 Mar). Biodiversity and evolution of primary carbon metabolism in Aspergillus nidulans and other Aspergillus spp.
Lee MK, et al. (2014 May). NsdD is a key repressor of asexual development in Aspergillus nidulans.
| Mitochondrial localization predictions | ||
|---|---|---|
| Predotar | TargetP | MitoProt |
 |
 |
 |
| Raw data
|
||
| Phobius transmembrane predictions
3 genes with posterior transmembrane prediction > 50% |
||
