FOG00397
EOG8Z08QB
GPP1
sce:GPP1

Genes: 25

Protein description
GPP1 constitutive


SGD Description
Constitutively expressed DL-glycerol-3-phosphate phosphatase; also known as glycerol-1-phosphatase; involved in glycerol biosynthesis, induced in response to both anaerobic and osmotic stress; GPP1 has a paralog, GPP2, that arose from the whole genome duplication


AspGD Description
Glycerol 3-phosphate phosphatase


References

Hirayama T, et al. (1995 Nov 15). Cloning and characterization of seven cDNAs for hyperosmolarity-responsive (HOR) genes of Saccharomyces cerevisiae.

Norbeck J, et al. (1996 Jun 7). Purification and characterization of two isoenzymes of DL-glycerol-3-phosphatase from Saccharomyces cerevisiae. Identification of the corresponding GPP1 and GPP2 genes and evidence for osmotic regulation of Gpp2p expression by the osmosensing mitogen-activated protein kinase signal transduction pathway.

Norbeck J, et al. (1997 Feb 28). Metabolic and regulatory changes associated with growth of Saccharomyces cerevisiae in 1.4 M NaCl. Evidence for osmotic induction of glycerol dissimilation via the dihydroxyacetone pathway.

Larsson T, et al. (1997 Mar-Apr). Identification of two-dimensional gel electrophoresis resolved yeast proteins by matrix-assisted laser desorption ionization mass spectrometry.

Costenoble R, et al. (2000 Dec). Microaerobic glycerol formation in Saccharomyces cerevisiae.

Siderius M, et al. (2000 Jun). The control of intracellular glycerol in Saccharomyces cerevisiae influences osmotic stress response and resistance to increased temperature.

Pahlman AK, et al. (2001 Feb 2). The yeast glycerol 3-phosphatases Gpp1p and Gpp2p are required for glycerol biosynthesis and differentially involved in the cellular responses to osmotic, anaerobic, and oxidative stress.

Nguyen HT, et al. (2004 Apr). Engineering of Saccharomyces cerevisiae for the production of L-glycerol 3-phosphate.

Sonderegger M, et al. (2004 Apr). Molecular basis for anaerobic growth of Saccharomyces cerevisiae on xylose, investigated by global gene expression and metabolic flux analysis.

Zhou W, et al. (2004 Jul 30). Global analyses of sumoylated proteins in Saccharomyces cerevisiae. Induction of protein sumoylation by cellular stresses.

Granath K, et al. (2005 Dec). The YIG1 (YPL201c) encoded protein is involved in regulating anaerobic glycerol metabolism in Saccharomyces cerevisiae.

Chi A, et al. (2007 Feb 13). Analysis of phosphorylation sites on proteins from Saccharomyces cerevisiae by electron transfer dissociation (ETD) mass spectrometry.

Wiebe MG, et al. (2008 Feb). Central carbon metabolism of Saccharomyces cerevisiae in anaerobic, oxygen-limited and fully aerobic steady-state conditions and following a shift to anaerobic conditions.

Popp A, et al. (2008 Jun 15). Fermentative production of L-glycerol 3-phosphate utilizing a Saccharomyces cerevisiae strain with an engineered glycerol biosynthetic pathway.

Bouwman J, et al. (2011 Jan). Metabolic regulation rather than de novo enzyme synthesis dominates the osmo-adaptation of yeast.

Starita LM, et al. (2012 Jan). Sites of ubiquitin attachment in Saccharomyces cerevisiae.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 1 genes with posterior transmembrane prediction > 50%

FOG00398
EOG8Z08QB
GPP1.2
sce:absent

Genes: 1

Protein description
GPP ang paralog?


Parent
paralog:FOG00397


AspGD Description
Has domain(s) with predicted hydrolase activity

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG00399
EOG8Z08QB
GPP2
sce:GPP2

Genes: 2

Protein description
GPP2 diauxic shift


Parent
paralog:FOG00397


SGD Description
DL-glycerol-3-phosphate phosphatase involved in glycerol biosynthesis; also known as glycerol-1-phosphatase; induced in response to hyperosmotic or oxidative stress, and during diauxic shift; GPP2 has a paralog, GPP1, that arose from the whole genome duplication


References

Hirayama T, et al. (1995 Nov 15). Cloning and characterization of seven cDNAs for hyperosmolarity-responsive (HOR) genes of Saccharomyces cerevisiae.

Norbeck J, et al. (1996 Jun 7). Purification and characterization of two isoenzymes of DL-glycerol-3-phosphatase from Saccharomyces cerevisiae. Identification of the corresponding GPP1 and GPP2 genes and evidence for osmotic regulation of Gpp2p expression by the osmosensing mitogen-activated protein kinase signal transduction pathway.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 1 genes with posterior transmembrane prediction > 50%

FOG00400
EOG8Z08QB
DOG1
sce:DOG1

Genes: 14

Protein description
DOG1


SGD Description
2-deoxyglucose-6-phosphate phosphatase; member of a family of low molecular weight phosphatases; confers 2-deoxyglucose resistance when overexpressed; DOG1 has a paralog, DOG2, that arose from a single-locus duplication; the last half of DOG1 and DOG2 are subject to gene conversions among S. cerevisiae, S. paradoxus, and S. mikatae


References

Sanz P, et al. (1994 Sep). Molecular characterization of a gene that confers 2-deoxyglucose resistance in yeast.

Randez-Gil F, et al. (1995 Oct). DOGR1 and DOGR2: two genes from Saccharomyces cerevisiae that confer 2-deoxyglucose resistance when overexpressed.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG00401
EOG8Z08QB
DOG2
sce:DOG2

Genes: 1

Parent
paralog:FOG00400


SGD Description
2-deoxyglucose-6-phosphate phosphatase; member of a family of low molecular weight phosphatases, induced by oxidative and osmotic stress, confers 2-deoxyglucose resistance when overexpressed; DOG2 has a paralog, DOG1, that arose from a single-locus duplication; the last half of DOG1 and DOG2 are subject to gene conversions among S. cerevisiae, S. paradoxus, and S. mikatae


References

Randez-Gil F, et al. (1995 Oct). DOGR1 and DOGR2: two genes from Saccharomyces cerevisiae that confer 2-deoxyglucose resistance when overexpressed.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG00402
EOG8Z08QB
DOG3
sce:absent

Genes: 1

Protein description
DOG


Parent
ohnolog?:FOG00400

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%

FOG00403

DOG4
sce:absent

Genes: 1

Protein description
DOG car paralog


Parent
paralog:FOG00400


Suggested Analysis
Has higher divergence when compared to Canar1_176493 in phylogenetic tree

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%