FOG00209
EOG8MSBG2

sce:POL31

Genes: 33

Protein description
DNA polymerase III delta


SGD Description
Subunit of DNA polymerase delta (polymerase III); essential for cell viability; involved in DNA replication and DNA repair; forms a complex with Rev3p, Rev7p and Pol32p; relocalizes to the cytosol in response to hypoxia


PomBase Description
DNA polymerase delta small subunit Cdc1


AspGD Description
DNA-directed DNA polymerase


References

Nurse P, et al. (1976 Jul 23). Genetic control of the cell division cycle in the fission yeast Schizosaccharomyces pombe.

Hirano T, et al. (1986 Nov). Isolation and characterization of Schizosaccharomyces pombe cutmutants that block nuclear division but not cytokinesis.

Grallert B, et al. (1991 Aug). Common genes and pathways in the regulation of the mitotic and meiotic cell cycles of Schizosaccharomyces pombe.

Ishiguro J, et al. (1993 Aug). A novel mutation involved in the mitotic checkpoint in the fission yeast Schizosaccharomyces pombe.

Takahashi K, et al. (1994 Oct). Fission yeast minichromosome loss mutants mis cause lethal aneuploidy and replication abnormality.

Jimenez J, et al. (1994 Oct 17). Ethanol-hypersensitive and ethanol-dependent cdc- mutants in Schizosaccharomyces pombe.

Sugimoto K, et al. (1995 Sep 11). HYS2, an essential gene required for DNA replication in Saccharomyces cerevisiae.

MacNeill SA, et al. (1996 Sep 2). The fission yeast Cdc1 protein, a homologue of the small subunit of DNA polymerase delta, binds to Pol3 and Cdc27.

Forsburg SL, et al. (1997 Nov). Mutational analysis of Cdc19p, a Schizosaccharomyces pombe MCM protein.

Zuo S, et al. (1997 Oct 14). DNA polymerase delta isolated from Schizosaccharomyces pombe contains five subunits.

Hashimoto K, et al. (1998 Jan 15). The second subunit of DNA polymerase III (delta) is encoded by the HYS2 gene in Saccharomyces cerevisiae.

Gerik KJ, et al. (1998 Jul 31). Characterization of the two small subunits of Saccharomyces cerevisiae DNA polymerase delta.

Reynolds N, et al. (1998 Oct). Cdm1, the smallest subunit of DNA polymerase d in the fission yeast Schizosaccharomyces pombe, is non-essential for growth and division.

Liu VF, et al. (1999 Feb). Mutator phenotype induced by aberrant replication.

Snaith HA, et al. (1999 Jul). Rereplication phenomenon in fission yeast requires MCM proteins and other S phase genes.

Zuo S, et al. (2000 Feb 18). Structure and activity associated with multiple forms of Schizosaccharomyces pombe DNA polymerase delta.

Forsburg SL, et al. (2000 Jul). Mitotic replication initiation proteins are not required for pre-meiotic S phase.

Kang HY, et al. (2000 Jul). Genetic analyses of Schizosaccharomyces pombe dna2(+) reveal that dna2 plays an essential role in Okazaki fragment metabolism.

Chen X, et al. (2000 Jun 9). Fidelity of eucaryotic DNA polymerase delta holoenzyme from Schizosaccharomyces pombe.

Griffiths D, et al. (2000 Mar). A novel mutant allele of the chromatin-bound fission yeast checkpoint protein Rad17 separates the DNA structure checkpoints.

Reynolds N, et al. (2000 Mar 1). Essential interaction between the fission yeast DNA polymerase delta subunit Cdc27 and Pcn1 (PCNA) mediated through a C-terminal p21(Cip1)-like PCNA binding motif.

Alleva JL, et al. (2000 Mar 14). In vitro reconstitution of the Schizosaccharomyces pombe alternative excision repair pathway.

Wang SW, et al. (2000 May). Cid1, a fission yeast protein required for S-M checkpoint control when DNA polymerase delta or epsilon is inactivated.

Johansson E, et al. (2001 Nov 23). Structure of DNA polymerase delta from Saccharomyces cerevisiae.

Bermudez VP, et al. (2002 Sep 27). The influence of the Cdc27 subunit on the properties of the Schizosaccharomyces pombe DNA polymerase delta.

Dahlén M, et al. (2003 May). Replication proteins influence the maintenance of telomere length and telomerase protein stability.

Sanchez Garcia J, et al. (2004). The C-terminal zinc finger of the catalytic subunit of DNA polymerase delta is responsible for direct interaction with the B-subunit.

Gray FC, et al. (2004 Dec 3). Mapping and mutation of the conserved DNA polymerase interaction motif (DPIM) located in the C-terminal domain of fission yeast DNA polymerase delta subunit Cdc27.

Kim J, et al. (2005). Contrasting effects of Elg1-RFC and Ctf18-RFC inactivation in the absence of fully functional RFC in fission yeast.

Locovei AM, et al. (2006 Nov 17). The CENP-B homolog, Abp1, interacts with the initiation protein Cdc23 (MCM10) and is required for efficient DNA replication in fission yeast.

Sanchez Garcia J, et al. (2009 Aug 17). Functional mapping of the fission yeast DNA polymerase delta B-subunit Cdc1 by site-directed and random pentapeptide insertion mutagenesis.

Schinko T, et al. (2010 Nov). Transcriptome analysis of nitrate assimilation in Aspergillus nidulans reveals connections to nitric oxide metabolism.

Van Damme P, et al. (2012 Jul 31). N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

Kuntz K, et al. (2013 Jan 23). Initiation of DNA damage responses through XPG-related nucleases.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Smialowska A, et al. (2014 Feb 7). RNAi mediates post-transcriptional repression of gene expression in fission yeast Schizosaccharomyces pombe.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 1 genes with posterior transmembrane prediction > 50%