Protein descriptionRPL7 Large ribosome protein subunit
SGD DescriptionRibosomal 60S subunit protein L7A; required for processing of 27SA3 pre-rRNA to 27SB pre-rRNA during assembly of large ribosomal subunit; depletion leads to a turnover of pre-rRNA; contains a conserved C-terminal Nucleic acid Binding Domain (NDB2); binds to Domain II of 25S and 5.8S rRNAs; homologous to mammalian ribosomal protein L7 and bacterial L30; RPL7A has a paralog, RPL7B, that arose from the whole genome duplication|Ribosomal 60S subunit protein L7B; required for processing of 27SA3 pre-rRNA to 27SB pre-rRNA during assembly of large ribosomal subunit; depletion leads to a turnover of pre-rRNA; contains a conserved C-terminal Nucleic acid Binding Domain (NDB2); binds to Domain II of 25S and 5.8S rRNAs; homologous to mammalian ribosomal protein L7 and bacterial L30; RPL7B has a paralog, RPL7A, that arose from the whole genome duplication
PomBase Description60S ribosomal protein L7
AspGD DescriptionOrtholog(s) have structural constituent of ribosome activity, role in cytoplasmic translation, maturation of LSU-rRNA and cell surface, cytosolic large ribosomal subunit, nucleolus, preribosome, large subunit precursor localization
References
Otaka E, et al. (1984). Yeast ribosomal proteins. VIII. Isolation of two proteins and sequence characterization of twenty-four proteins from cytoplasmic ribosomes.
Mizuta K, et al. (1992 Mar 11). Yeast ribosomal proteins: XIII. Saccharomyces cerevisiae YL8A gene, interrupted with two introns, encodes a homolog of mammalian L7.
Takakura H, et al. (1992 Mar 15). NH2-terminal acetylation of ribosomal proteins of Saccharomyces cerevisiae.
Mizuta K, et al. (1995 Jun). The evolutionary relationships between homologs of ribosomal YL8 protein and YL8-like proteins.
Nam K, et al. (1997 Feb). Severe growth defect in a Schizosaccharomyces pombe mutant defective in intron lariat degradation.
Planta RJ, et al. (1998 Mar 30). The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae.
Arnold RJ, et al. (1999 Dec 24). The action of N-terminal acetyltransferases on yeast ribosomal proteins.
Habara Y, et al. (2001 May). Mutation in the prp12+ gene encoding a homolog of SAP130/SF3b130 causes differential inhibition of pre-mRNA splicing and arrest of cell-cycle progression in Schizosaccharomyces pombe.
Spahn CM, et al. (2001 Nov 2). Structure of the 80S ribosome from Saccharomyces cerevisiae--tRNA-ribosome and subunit-subunit interactions.
Spahn CM, et al. (2004 Mar 10). Domain movements of elongation factor eEF2 and the eukaryotic 80S ribosome facilitate tRNA translocation.
Perreault A, et al. (2007 Mar 9). Regulation of the nuclear poly(A)-binding protein by arginine methylation in fission yeast.
Lemieux C, et al. (2009 Jun). Cotranscriptional recruitment of the nuclear poly(A)-binding protein Pab2 to nascent transcripts and association with translating mRNPs.
Keller C, et al. (2010 Jun). Proteomic and functional analysis of the noncanonical poly(A) polymerase Cid14.
Ben-Shem A, et al. (2010 Nov 26). Crystal structure of the eukaryotic ribosome.
Stewart EV, et al. (2011 Apr 22). Yeast SREBP cleavage activation requires the Golgi Dsc E3 ligase complex.
Ben-Shem A, et al. (2011 Dec 16). The structure of the eukaryotic ribosome at 3.0 Å resolution.
Snaith HA, et al. (2011 Jul 1). Characterization of Mug33 reveals complementary roles for actin cable-dependent transport and exocyst regulators in fission yeast exocytosis.
Van Damme P, et al. (2012 Jul 31). N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.
Fontebasso Y, et al. (2013 Dec). The conserved Fanconi anemia nuclease Fan1 and the SUMO E3 ligase Pli1 act in two novel Pso2-independent pathways of DNA interstrand crosslink repair in yeast.
Saito Y, et al. (2014). RNase MRP cleaves pre-tRNASer-Met in the tRNA maturation pathway.
Anver S, et al. (2014 Aug). Yeast X-chromosome-associated protein 5 (Xap5) functions with H2A.Z to suppress aberrant transcripts.
Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).
Ban N, et al. (2014 Feb). A new system for naming ribosomal proteins.
Rallis C, et al. (2014 Feb 15). Systematic screen for mutants resistant to TORC1 inhibition in fission yeast reveals genes involved in cellular ageing and growth.
Mathiassen SG, et al. (2015 Aug 21). A Two-step Protein Quality Control Pathway for a Misfolded DJ-1 Variant in Fission Yeast.
Murray J, et al. (2016 May 9). Structural characterization of ribosome recruitment and translocation by type IV IRES.
Dudin O, et al. (2017 Apr). A systematic screen for morphological abnormalities during fission yeast sexual reproduction identifies a mechanism of actin aster formation for cell fusion.
Protein descriptionNucleolar protein similar to large ribosomal subunit L7 proteins
Parentparalog:FOG00007
SGD DescriptionNucleolar protein similar to large ribosomal subunit L7 proteins; constituent of 66S pre-ribosomal particles; plays an essential role in processing of precursors to the large ribosomal subunit RNAs; binds junction of ITS2 and ITS2-proximal stem between the 3' end of 5.8S rRNA and the 5' end of 25S rRNA
References
Zhang YP, et al. (1992 Sep). LEU2 gene homolog in Kluyveromyces lactis.
Lalo D, et al. (1993). Two yeast chromosomes are related by a fossil duplication of their centromeric regions.
Lalo D, et al. (1993 Oct). Two distinct yeast proteins are related to the mammalian ribosomal polypeptide L7.
Lalo D, et al. (1994 Apr). Organization of the centromeric region of chromosome XIV in Saccharomyces cerevisiae.
Dunbar DA, et al. (2000 Nov 21). A nucleolar protein related to ribosomal protein L7 is required for an early step in large ribosomal subunit biogenesis.
Chi A, et al. (2007 Feb 13). Analysis of phosphorylation sites on proteins from Saccharomyces cerevisiae by electron transfer dissociation (ETD) mass spectrometry.
Van Damme P, et al. (2012 Jul 31). N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.