FOG19569
EOG805QFX

sce:MON2

Genes: 33

SGD Description
Protein with a role in endocytosis and vacuole integrity; peripheral membrane protein; interacts with and negatively regulates Arl1p; localizes to the endosome; member of the Sec7p family of proteins


PomBase Description
guanyl-nucleotide exchange factor (predicted)


AspGD Description
Ortholog(s) have guanyl-nucleotide exchange factor activity and role in Golgi to endosome transport, endocytosis, protein targeting to vacuole


References

Bonangelino CJ, et al. (2002 Jul). Genomic screen for vacuolar protein sorting genes in Saccharomyces cerevisiae.

Jochum A, et al. (2002 Jul). Yeast Ysl2p, homologous to Sec7 domain guanine nucleotide exchange factors, functions in endocytosis and maintenance of vacuole integrity and interacts with the Arf-Like small GTPase Arl1p.

Wicky S, et al. (2004 Sep). Molecular interactions of yeast Neo1p, an essential member of the Drs2 family of aminophospholipid translocases, and its role in membrane trafficking within the endomembrane system.

Gruhler A, et al. (2005 Mar). Quantitative phosphoproteomics applied to the yeast pheromone signaling pathway.

Efe JA, et al. (2005 Oct 15). Yeast Mon2p is a highly conserved protein that functions in the cytoplasm-to-vacuole transport pathway and is required for Golgi homeostasis.

Gillingham AK, et al. (2006 Jan 27). Mon2, a relative of large Arf exchange factors, recruits Dop1 to the Golgi apparatus.

Wilson-Grady JT, et al. (2008 Mar). Phosphoproteome analysis of fission yeast.

Beltrao P, et al. (2009 Jun 16). Evolution of phosphoregulation: comparison of phosphorylation patterns across yeast species.

Van Damme P, et al. (2012 Jul 31). N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 25 genes with posterior transmembrane prediction > 50%