FOG19465
EOG80CG21

sce:CBC2

Genes: 33

SGD Description
Small subunit of the heterodimeric cap binding complex with Sto1p; interacts with Npl3p, possibly to package mRNA for export from the nucleus; may have a role in telomere maintenance; contains an RNA-binding motif


PomBase Description
nuclear cap-binding complex small subunit (predicted)


AspGD Description
Ortholog(s) have RNA cap binding activity, role in mRNA splicing, via spliceosome and commitment complex, cytosol, mitotic spindle, nuclear cap binding complex localization


References

Colot HV, et al. (1996 Jul 1). The yeast splicing factor Mud13p is a commitment complex component and corresponds to CBP20, the small subunit of the nuclear cap-binding complex.

Görlich D, et al. (1996 Oct 4). Importin provides a link between nuclear protein import and U snRNA export.

Lewis JD, et al. (1996 Sep 1). A yeast cap binding protein complex (yCBC) acts at an early step in pre-mRNA splicing.

McKee AH, et al. (1997 Jul). Mutations in Saccharomyces cerevisiae that block meiotic prophase chromosome metabolism and confer cell cycle arrest at pachytene identify two new meiosis-specific genes SAE1 and SAE3.

Fortes P, et al. (1999 Oct). Genetic and physical interactions involving the yeast nuclear cap-binding complex.

Rigaut G, et al. (1999 Oct). A generic protein purification method for protein complex characterization and proteome exploration.

Shen EC, et al. (2000 Aug 4). 7The yeast mRNA-binding protein Npl3p interacts with the cap-binding complex.

Kushner DB, et al. (2003 Dec 23). Systematic, genome-wide identification of host genes affecting replication of a positive-strand RNA virus.

Baron-Benhamou J, et al. (2003 Jun). The interaction of the cap-binding complex (CBC) with eIF4G is dispensable for translation in yeast.

Gao Q, et al. (2005 Mar 22). Cap-binding protein 1-mediated and eukaryotic translation initiation factor 4E-mediated pioneer rounds of translation in yeast.

Kuai L, et al. (2005 Sep 27). A nuclear degradation pathway controls the abundance of normal mRNAs in Saccharomyces cerevisiae.

Vasiljeva L, et al. (2006 Jan 20). Nrd1 interacts with the nuclear exosome for 3' processing of RNA polymerase II transcripts.

Hernández H, et al. (2006 Jun). Subunit architecture of multimeric complexes isolated directly from cells.

Van Damme P, et al. (2012 Jul 31). N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Zhou Y, et al. (2015 May 20). The fission yeast MTREC complex targets CUTs and unspliced pre-mRNAs to the nuclear exosome.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%