FOG19459
EOG80CG34

sce:VPS75

Genes: 23

SGD Description
NAP family histone chaperone; binds to histones and Rtt109p, stimulating histone acetyltransferase activity; possesses nucleosome assembly activity in vitro; proposed role in vacuolar protein sorting and in double-strand break repair; protein abundance increases in response to DNA replication stress; relocalizes to the cytosol in response to hypoxia


References

Bonangelino CJ, et al. (2002 Jul). Genomic screen for vacuolar protein sorting genes in Saccharomyces cerevisiae.

Han J, et al. (2007 Feb 2). Rtt109 acetylates histone H3 lysine 56 and functions in DNA replication.

Tsubota T, et al. (2007 Mar 9). Histone H3-K56 acetylation is catalyzed by histone chaperone-dependent complexes.

Mitochondrial localization predictions
Predotar TargetP MitoProt
Raw data
Phobius transmembrane predictions
0 genes with posterior transmembrane prediction > 50%