FOG19327
EOG80RZ1V

sce:SHE2

Genes: 6

SGD Description
RNA-binding protein that binds specific mRNAs and interacts with She3p; part of the mRNA localization machinery that restricts accumulation of certain proteins to the bud; binds to ER-derived membranes and targets mRNAs to cortical ER


References

Bertrand E, et al. (1998 Oct). Localization of ASH1 mRNA particles in living yeast.

Beach DL, et al. (1999 Jun 3). Localization and anchoring of mRNA in budding yeast.

Münchow S, et al. (1999 May). Association of the class V myosin Myo4p with a localised messenger RNA in budding yeast depends on She proteins.

Long RM, et al. (2000 Dec 1). She2p is a novel RNA-binding protein that recruits the Myo4p-She3p complex to ASH1 mRNA.

Takizawa PA, et al. (2000 May 9). The myosin motor, Myo4p, binds Ash1 mRNA via the adapter protein, She3p.

Böhl F, et al. (2000 Oct 16). She2p, a novel RNA-binding protein tethers ASH1 mRNA to the Myo4p myosin motor via She3p.

Kruse C, et al. (2002 Dec 23). Ribonucleoprotein-dependent localization of the yeast class V myosin Myo4p.

Estrada P, et al. (2003 Dec 22). Myo4p and She3p are required for cortical ER inheritance in Saccharomyces cerevisiae.

Gonsalvez GB, et al. (2003 Nov). RNA-protein interactions promote asymmetric sorting of the ASH1 mRNA ribonucleoprotein complex.

Shepard KA, et al. (2003 Sep 30). Widespread cytoplasmic mRNA transport in yeast: identification of 22 bud-localized transcripts using DNA microarray analysis.

Niessing D, et al. (2004 Nov 12). She2p is a novel RNA binding protein with a basic helical hairpin motif.

Gonsalvez GB, et al. (2004 Oct 29). ASH1 mRNA anchoring requires reorganization of the Myo4p-She3p-She2p transport complex.

Olivier C, et al. (2005 Jun). Identification of a conserved RNA motif essential for She2p recognition and mRNA localization to the yeast bud.

Schmid M, et al. (2006 Aug 8). Coordination of endoplasmic reticulum and mRNA localization to the yeast bud.

Du TG, et al. (2008 Aug). Nuclear transit of the RNA-binding protein She2 is required for translational control of localized ASH1 mRNA.

Shen Z, et al. (2009 Apr). Nuclear shuttling of She2p couples ASH1 mRNA localization to its translational repression by recruiting Loc1p and Puf6p.

Müller M, et al. (2009 Nov). Formation of She2p tetramers is required for mRNA binding, mRNP assembly, and localization.

Shen Z, et al. (2010 Sep 1). Cotranscriptional recruitment of She2p by RNA pol II elongation factor Spt4-Spt5/DSIF promotes mRNA localization to the yeast bud.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%