FOG19162
EOG81894J

sce:PRP6

Genes: 33

SGD Description
Splicing factor; component of the U4/U6-U5 snRNP complex


PomBase Description
U4/U6 x U5 tri-snRNP complex subunit Prp1


AspGD Description
Ortholog(s) have role in mRNA cis splicing, via spliceosome and U4/U6 x U5 tri-snRNP complex localization


References

Potashkin J, et al. (1989 Feb). Pre-mRNA splicing mutants of Schizosaccharomyces pombe.

Potashkin J, et al. (1989 Oct 11). Splicing of the U6 RNA precursor is impaired in fission yeast pre-mRNA splicing mutants.

Legrain P, et al. (1990 Sep). The molecular characterization of PRP6 and PRP9 yeast genes reveals a new cysteine/histidine motif common to several splicing factors.

Rosenberg GH, et al. (1991 Apr). prp4 from Schizosaccharomyces pombe, a mutant deficient in pre-mRNA splicing isolated using genes containing artificial introns.

Lundgren K, et al. (1996 Jul). A connection between pre-mRNA splicing and the cell cycle in fission yeast: cdc28+ is allelic with prp8+ and encodes an RNA-dependent ATPase/helicase.

Urushiyama S, et al. (1996 Nov 27). Isolation of novel pre-mRNA splicing mutants of Schizosaccharomyces pombe.

Urushiyama S, et al. (1997 Sep). The prp1+ gene required for pre-mRNA splicing in Schizosaccharomyces pombe encodes a protein that contains TPR motifs and is similar to Prp6p of budding yeast.

Gottschalk A, et al. (1999 Aug 16). Identification by mass spectrometry and functional analysis of novel proteins of the yeast [U4/U6.U5] tri-snRNP.

Schwelnus W, et al. (2001 Jan). Fission yeast Prp4p kinase regulates pre-mRNA splicing by phosphorylating a non-SR-splicing factor.

Habara Y, et al. (2001 May). Mutation in the prp12+ gene encoding a homolog of SAP130/SF3b130 causes differential inhibition of pre-mRNA splicing and arrest of cell-cycle progression in Schizosaccharomyces pombe.

Carnahan RH, et al. (2005 Mar). Dim1p is required for efficient splicing and export of mRNA encoding lid1p, a component of the fission yeast anaphase-promoting complex.

Bottner CA, et al. (2005 Sep). Multiple genetic and biochemical interactions of Brr2, Prp8, Prp31, Prp1 and Prp4 kinase suggest a function in the control of the activation of spliceosomes in Schizosaccharomyces pombe.

Wilson-Grady JT, et al. (2008 Mar). Phosphoproteome analysis of fission yeast.

Häcker I, et al. (2008 Nov). Localization of Prp8, Brr2, Snu114 and U4/U6 proteins in the yeast tri-snRNP by electron microscopy.

Bernard P, et al. (2010 Mar). Splicing factor Spf30 assists exosome-mediated gene silencing in fission yeast.

Lützelberger M, et al. (2010 Mar). The N-terminus of Prp1 (Prp6/U5-102 K) is essential for spliceosome activation in vivo.

Wendland J, et al. (2011 Dec). Genome evolution in the eremothecium clade of the Saccharomyces complex revealed by comparative genomics.

Ren L, et al. (2011 Feb 28). Systematic two-hybrid and comparative proteomic analyses reveal novel yeast pre-mRNA splicing factors connected to Prp19.

Watanabe N, et al. (2012 Feb 3). Characterization of the ptr5+ gene involved in nuclear mRNA export in fission yeast.

Shim YS, et al. (2012 Nov 28). Hrp3 controls nucleosome positioning to suppress non-coding transcription in eu- and heterochromatin.

Banerjee S, et al. (2013 Aug). Splicing functions and global dependency on fission yeast slu7 reveal diversity in spliceosome assembly.

Grenier St-Sauveur V, et al. (2013 Dec). Poly(A) tail-mediated gene regulation by opposing roles of Nab2 and Pab2 nuclear poly(A)-binding proteins in pre-mRNA decay.

Livesay SB, et al. (2013 Nov). Structural and functional characterization of the N terminus of Schizosaccharomyces pombe Cwf10.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Gal C, et al. (2016 Jan). Abo1, a conserved bromodomain AAA-ATPase, maintains global nucleosome occupancy and organisation.

Yadav S, et al. (2016 Jun). Mutant allele of rna14 in fission yeast affects pre-mRNA splicing.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%