FOG19095
EOG81G1KB

sce:PEX1

Genes: 32

SGD Description
AAA-peroxin; heterodimerizes with AAA-peroxin Pex6p and participates in the recycling of peroxisomal signal receptor Pex5p from the peroxisomal membrane to the cystosol; induced by oleic acid and upregulated during anaerobiosis


PomBase Description
AAA family ATPase Pex1 (predicted)


AspGD Description
Ortholog(s) have ATPase activity, protein heterodimerization activity, role in fatty acid metabolic process, protein import into peroxisome matrix, receptor recycling and cytosol, peroxisomal membrane localization


References

Erdmann R, et al. (1991 Feb 8). PAS1, a yeast gene required for peroxisome biogenesis, encodes a member of a novel family of putative ATPases.

Krause T, et al. (1994 Dec). Effect of site-directed mutagenesis of conserved lysine residues upon Pas1 protein function in peroxisome biogenesis.

Platta HW, et al. (2005 Aug). Functional role of the AAA peroxins in dislocation of the cycling PTS1 receptor back to the cytosol.

Birschmann I, et al. (2005 Jan). Structural and functional analysis of the interaction of the AAA-peroxins Pex1p and Pex6p.

Rosenkranz K, et al. (2006 Aug). Functional association of the AAA complex and the peroxisomal importomer.

Kiel JA, et al. (2006 Oct). PEX genes in fungal genomes: common, rare or redundant.

Hynes MJ, et al. (2008 Mar). Genetic analysis of the role of peroxisomes in the utilization of acetate and fatty acids in Aspergillus nidulans.

Salazar M, et al. (2009 Dec). Uncovering transcriptional regulation of glycerol metabolism in Aspergilli through genome-wide gene expression data analysis.

Crane DI, et al. (2014 Apr). Revisiting the neuropathogenesis of Zellweger syndrome.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Guo L, et al. (2016 Oct 13). Global Fitness Profiling Identifies Arsenic and Cadmium Tolerance Mechanisms in Fission Yeast.

Lee J, et al. (2017 Feb 20). Chromatin remodeller Fun30^Fft3 induces nucleosome disassembly to facilitate RNA polymerase II elongation.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%