FOG19092
EOG81G1M1

sce:NOB1

Genes: 33

SGD Description
Protein involved in proteasomal and 40S ribosomal subunit biogenesis; required for cleavage of the 20S pre-rRNA to generate the mature 18S rRNA; cleavage is activated by Fun12p, a GTPase and translation initiation factor; relocalizes from nucleus to nucleolus upon DNA replication stress


PomBase Description
ribosome biogenesis protein Nob1 (predicted)


AspGD Description
Ortholog(s) have nucleus localization


References

Tone Y, et al. (2002 Dec 15). Nob1p is required for biogenesis of the 26S proteasome and degraded upon its maturation in Saccharomyces cerevisiae.

Chen D, et al. (2003 Jan). Global transcriptional responses of fission yeast to environmental stress.

Fatica A, et al. (2003 Mar). Nob1p is required for cleavage of the 3' end of 18S rRNA.

Schäfer T, et al. (2003 Mar 17). The path from nucleolar 90S to cytoplasmic 40S pre-ribosomes.

Vanrobays E, et al. (2004 Apr). Dim2p, a KH-domain protein required for small ribosomal subunit synthesis.

Fatica A, et al. (2004 Nov). PIN domain of Nob1p is required for D-site cleavage in 20S pre-rRNA.

Wendland J, et al. (2011 Dec). Genome evolution in the eremothecium clade of the Saccharomyces complex revealed by comparative genomics.

Zhang K, et al. (2011 Mar 25). Clr4/Suv39 and RNA quality control factors cooperate to trigger RNAi and suppress antisense RNA.

Van Damme P, et al. (2012 Jul 31). N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%