FOG19052
EOG81JWTR

sce:AIM14

Genes: 27

SGD Description
NADPH oxidase localized to the perinuclear ER; produces superoxide from NADPH; overexpression causes MCA1 dependent apoptosis; likely involved in superoxide-mediated regulation of the actin cytoskeleton; member of a conserved superfamily of NADPH oxidases (NOX enzymes); has similarity to iron/copper reductases (FRE1-8), particularly Fre8p


References

Kim H, et al. (2006 Jul 25). A global topology map of the Saccharomyces cerevisiae membrane proteome.

Fleischer TC, et al. (2006 May 15). Systematic identification and functional screens of uncharacterized proteins associated with eukaryotic ribosomal complexes.

Hess DC, et al. (2009 Mar). Computationally driven, quantitative experiments discover genes required for mitochondrial biogenesis.

Van Damme P, et al. (2012 Jul 31). N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 27 genes with posterior transmembrane prediction > 50%