FOG18866
EOG82283K

sce:TIP41

Genes: 31

SGD Description
Protein that interacts with Tap42p, which regulates PP2A; component of the TOR (target of rapamycin) signaling pathway; protein abundance increases in response to DNA replication stress


PomBase Description
TIP41-like type 2a phosphatase regulator Tip41


AspGD Description
Ortholog(s) have role in TOR signaling, positive regulation of protein phosphatase type 2A activity, signal transduction involved in cellular response to ammonium ion and cytosol, nucleus localization


References

Lisowsky T, et al. (1996 Dec). Removal of an intron with unique 3' branch site creates an amino-terminal protein sequence directing the scERV1 gene product to mitochondria.

Jacinto E, et al. (2001 Nov). TIP41 interacts with TAP42 and negatively regulates the TOR signaling pathway.

Dunn CD, et al. (2003 Sep). Suppression of a defect in mitochondrial protein import identifies cytosolic proteins required for viability of yeast cells lacking mitochondrial DNA.

Santhanam A, et al. (2004 Oct). PP2A phosphatase activity is required for stress and Tor kinase regulation of yeast stress response factor Msn2p.

Fenyvuesvolgyi C, et al. (2005 Dec 15). Fission yeast homologue of Tip41-like proteins regulates type 2A phosphatases and responses to nitrogen sources.

Fitzgibbon GJ, et al. (2005 Sep). Genetic analysis of the TOR pathway in Aspergillus nidulans.

Hanyu Y, et al. (2009 May). Schizosaccharomyces pombe cell division cycle under limited glucose requires Ssp1 kinase, the putative CaMKK, and Sds23, a PP2A-related phosphatase inhibitor.

Arita Y, et al. (2011 May). Microarray-based target identification using drug hypersensitive fission yeast expressing ORFeome.

Szilágyi M, et al. (2013 Jan). Transcriptome changes initiated by carbon starvation in Aspergillus nidulans.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Chen JS, et al. (2014 Dec 31). Identification of new players in cell division, DNA damage response, and morphogenesis through construction of Schizosaccharomyces pombe deletion strains.

Kovács B, et al. (2014 Sep). Penicillium antifungal protein (PAF) is involved in the apoptotic and autophagic processes of the producer Penicillium chrysogenum.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%