FOG18789
EOG8280J5

sce:SWD1

Genes: 33

SGD Description
Subunit of the COMPASS (Set1C) complex; COMPASS methylates histone H3 on lysine 4 and is required in transcriptional silencing near telomeres; WD40 beta propeller superfamily member with similarity to mammalian Rbbp7


PomBase Description
Set1C complex subunit Swd1


AspGD Description
Ortholog(s) have role in G2/M transition of mitotic cell cycle, histone H3-K4 methylation, positive regulation of mitotic nuclear division and Set1C/COMPASS complex, cytosol localization


References

Clark MW, et al. (1994 Apr). Sequencing of chromosome I of Saccharomyces cerevisiae: analysis of the 42 kbp SPO7-CENI-CDC15 region.

Roguev A, et al. (2001 Dec 17). The Saccharomyces cerevisiae Set1 complex includes an Ash2 homologue and methylates histone 3 lysine 4.

Miller T, et al. (2001 Nov 6). COMPASS: a complex of proteins associated with a trithorax-related SET domain protein.

Krogan NJ, et al. (2002 Mar 29). COMPASS, a histone H3 (Lysine 4) methyltransferase required for telomeric silencing of gene expression.

Sundin BA, et al. (2004 Jul 15). Localization of proteins that are coordinately expressed with Cln2 during the cell cycle.

Govindaraghavan M, et al. (2014 Aug). The Set1/COMPASS histone H3 methyltransferase helps regulate mitosis with the CDK1 and NIMA mitotic kinases in Aspergillus nidulans.

Mitochondrial localization predictions
Predotar TargetP MitoProt
Raw data
Phobius transmembrane predictions
0 genes with posterior transmembrane prediction > 50%