FOG18753
EOG82BVS0

sce:RCM1

Genes: 32

SGD Description
rRNA m5C methyltransferase; methylates cytosine at position 2278 of 25S rRNA while Nop2p methylates cytosine at position 2870; contains seven beta-strand methyltransferase motif; localized to the nucleolus; interacts with Trm112p; homolog of NSUN5A, a human gene which is deleted in Williams-Beuren Syndrome


PomBase Description
tRNA (cytosine-5-)-methyltransferase (predicted)


AspGD Description
Ortholog(s) have rRNA (cytosine-C5-)-methyltransferase activity, role in rRNA base methylation and nucleolus localization


References

Brachat A, et al. (2000 Feb). Analysis of deletion phenotypes and GFP fusions of 21 novel Saccharomyces cerevisiae open reading frames.

Sardana R, et al. (2012 Nov). The methyltransferase adaptor protein Trm112 is involved in biogenesis of both ribosomal subunits.

Sharma S, et al. (2013 Oct). Yeast Nop2 and Rcm1 methylate C2870 and C2278 of the 25S rRNA, respectively.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%