FOG18734
EOG82BVVT

sce:DOT5

Genes: 32

SGD Description
Nuclear thiol peroxidase; functions as an alkyl-hydroperoxide reductase during post-diauxic growth


PomBase Description
thioredoxin peroxidase Bcp1


AspGD Description
Ortholog(s) have thioredoxin peroxidase activity, role in cell redox homeostasis, cellular response to oxidative stress and cytosol, nucleus localization


References

Singer MS, et al. (1998 Oct). Identification of high-copy disruptors of telomeric silencing in Saccharomyces cerevisiae.

Park SG, et al. (2000 Feb 25). Distinct physiological functions of thiol peroxidase isoenzymes in Saccharomyces cerevisiae.

Cha MK, et al. (2003 Jul 4). Nuclear thiol peroxidase as a functional alkyl-hydroperoxide reductase necessary for stationary phase growth of Saccharomyces cerevisiae.

Izawa S, et al. (2004 Mar). Nuclear thioredoxin peroxidase Dot5 in Saccharomyces cerevisiae: roles in oxidative stress response and disruption of telomeric silencing.

Choi J, et al. (2005 Dec 1). Crystal structure of the C107S/C112S mutant of yeast nuclear 2-Cys peroxiredoxin.

Choi J, et al. (2005 Jul 1). Crystallization and preliminary X-ray analysis of a truncated mutant of yeast nuclear thiol peroxidase, a novel atypical 2-Cys peroxiredoxin.

Kang GY, et al. (2009 Feb). Overexpression of bacterioferritin comigratory protein (Bcp) enhances viability and reduced glutathione level in the fission yeast under stress.

Beltrao P, et al. (2009 Jun 16). Evolution of phosphoregulation: comparison of phosphorylation patterns across yeast species.

Sato I, et al. (2009 Mar 20). The glutathione system of Aspergillus nidulans involves a fungus-specific glutathione S-transferase.

Kim JS, et al. (2010 Mar). Distinct functional roles of peroxiredoxin isozymes and glutathione peroxidase from fission yeast, Schizosaccharomyces pombe.

Paulo E, et al. (2014 Apr). A genetic approach to study H2O2 scavenging in fission yeast--distinct roles of peroxiredoxin and catalase.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Sideri T, et al. (2014 Dec 1). Parallel profiling of fission yeast deletion mutants for proliferation and for lifespan during long-term quiescence.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%