FOG18621
EOG82NGG1

sce:absent

Genes: 33

AspGD Description
Ortholog(s) have 3-hydroxyphenylacetate 6-hydroxylase activity|Has domain(s) with predicted electron carrier activity, heme binding, iron ion binding, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen activity and role in oxidation-reduction process|Has domain(s) with predicted electron carrier activity, heme binding, iron ion binding, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen activity and role in oxidation-reduction process|Ortholog(s) have phenylacetate hydroxylase activity and role in penicillin biosynthetic process, phenylacetate catabolic process


References

Mingot JM, et al. (1999 May 21). Disruption of phacA, an Aspergillus nidulans gene encoding a novel cytochrome P450 monooxygenase catalyzing phenylacetate 2-hydroxylation, results in penicillin overproduction.

Rodríguez-Sáiz M, et al. (2001 Oct). Reduced function of a phenylacetate-oxidizing cytochrome p450 caused strong genetic improvement in early phylogeny of penicillin-producing strains.

Ferrer-Sevillano F, et al. (2007 Mar). Novel phacB-encoded cytochrome P450 monooxygenase from Aspergillus nidulans with 3-hydroxyphenylacetate 6-hydroxylase and 3,4-dihydroxyphenylacetate 6-hydroxylase activities.

Kelly DE, et al. (2009 Mar). The CYPome (Cytochrome P450 complement) of Aspergillus nidulans.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 16 genes with posterior transmembrane prediction > 50%