FOG18406
EOG834TP9

sce:YPT11

Genes: 10

SGD Description
Rab GTPase; Myo2p-binding protein implicated in mother-to-bud transport of cortical endoplasmic reticulum (ER), late Golgi, and mitochondria during cell division; function is regulated at multiple levels; abundance of active Ypt11p forms is controlled by phosphorylation status and degradation; normally a low-abundance protein whose ER localization is only detected when protein is highly over expressed


References

Calero M, et al. (2002 Jan 18). Saccharomyces cerevisiae Pra1p/Yip3p interacts with Yip1p and Rab proteins.

Calero M, et al. (2002 Mar 27). Identification of the novel proteins Yip4p and Yip5p as Rab GTPase interacting factors.

Itoh T, et al. (2002 Nov). Complex formation with Ypt11p, a rab-type small GTPase, is essential to facilitate the function of Myo2p, a class V myosin, in mitochondrial distribution in Saccharomyces cerevisiae.

Kellis M, et al. (2003 May 15). Sequencing and comparison of yeast species to identify genes and regulatory elements.

Itoh T, et al. (2004 Jul 7). Mmr1p is a mitochondrial factor for Myo2p-dependent inheritance of mitochondria in the budding yeast.

Boldogh IR, et al. (2004 Sep). A type V myosin (Myo2p) and a Rab-like G-protein (Ypt11p) are required for retention of newly inherited mitochondria in yeast cells during cell division.

Buvelot Frei S, et al. (2006 Oct). Bioinformatic and comparative localization of Rab proteins reveals functional insights into the uncharacterized GTPases Ypt10p and Ypt11p.

Frederick RL, et al. (2008 Feb). Multiple pathways influence mitochondrial inheritance in budding yeast.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%