FOG18300
EOG83BK85

sce:DOC1

Genes: 34

SGD Description
Processivity factor; required for the ubiquitination activity of the anaphase promoting complex (APC), mediates the activity of the APC by contributing to substrate recognition; involved in cyclin proteolysis; contains a conserved DOC1 homology domain


PomBase Description
anaphase-promoting complex substrate recognition subunit Apc10


AspGD Description
Ortholog of A. nidulans FGSC A4 : AN0911, A. fumigatus Af293 : Afu1g15770, A. oryzae RIB40 : AO090005001123, Aspergillus wentii : Aspwe1_0039951 and Aspergillus sydowii : Aspsy1_0267314


References

Hwang LH, et al. (1997 Oct). A novel yeast screen for mitotic arrest mutants identifies DOC1, a new gene involved in cyclin proteolysis.

Au SW, et al. (2002 Mar 1). Implications for the ubiquitination reaction of the anaphase-promoting complex from the crystal structure of the Doc1/Apc10 subunit.

Carroll CW, et al. (2002 Nov). The Doc1 subunit is a processivity factor for the anaphase-promoting complex.

Passmore LA, et al. (2003 Feb 17). Doc1 mediates the activity of the anaphase-promoting complex by contributing to substrate recognition.

Kellis M, et al. (2003 May 15). Sequencing and comparison of yeast species to identify genes and regulatory elements.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 1 genes with posterior transmembrane prediction > 50%