FOG18174
EOG83R23D

sce:TRS85

Genes: 34

SGD Description
Component of transport protein particle (TRAPP) complex III; TRAPPIII is a multimeric guanine nucleotide-exchange factor for the GTPase Ypt1p, regulating endosome-Golgi traffic and required for membrane expansion during autophagy and the CVT pathway; directs Ypt1p to the PAS; late post-replication meiotic role


PomBase Description
TRAPP complex subunit Trs85a (predicted)|TRAPP complex subunit Trs85b (predicted)


AspGD Description
Putative TRAPP complex subunit; expression enhanced by maltose


References

Kaytor MD, et al. (1995 Sep 30). GSG1, a yeast gene required for sporulation.

Sacher M, et al. (1998 May 1). TRAPP, a highly conserved novel complex on the cis-Golgi that mediates vesicle docking and fusion.

Sacher M, et al. (2000 Feb). Identification and characterization of five new subunits of TRAPP.

Sacher M, et al. (2001 Feb). TRAPP I implicated in the specificity of tethering in ER-to-Golgi transport.

Nazarko TY, et al. (2005 Apr). Trs85 is required for macroautophagy, pexophagy and cytoplasm to vacuole targeting in Yarrowia lipolytica and Saccharomyces cerevisiae.

Meiling-Wesse K, et al. (2005 Sep 30). Trs85 (Gsg1), a component of the TRAPP complexes, is required for the organization of the preautophagosomal structure during selective autophagy via the Cvt pathway.

Lynch-Day MA, et al. (2010 Apr 27). Trs85 directs a Ypt1 GEF, TRAPPIII, to the phagophore to promote autophagy.

Pan X, et al. (2012 Nov 23). Identification of novel genes involved in DNA damage response by screening a genome-wide Schizosaccharomyces pombe deletion library.

Pinar M, et al. (2013 Jul). Live-cell imaging of Aspergillus nidulans autophagy: RAB1 dependence, Golgi independence and ER involvement.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Mitochondrial localization predictions
Predotar TargetP MitoProt
Raw data
Phobius transmembrane predictions
11 genes with posterior transmembrane prediction > 50%