FOG18091
EOG83XSKH

sce:NOC3

Genes: 33

SGD Description
Subunit of a nuclear complex with Noc2p and pre-replicative complexes; the Noc2p-Noc3p complex binds to 66S ribosomal precursors to mediate their maturation and intranuclear transport; binds to chromatin at active replication origins, and is required for pre-RC formation and maintenance during DNA replication licensing


PomBase Description
Noc2p-Noc3p complex subunit Noc3


AspGD Description
Ortholog(s) have chromatin binding activity and role in DNA replication initiation, pre-replicative complex assembly involved in nuclear cell cycle DNA replication, rRNA processing, response to drug


References

Milkereit P, et al. (2001 May 18). Maturation and intranuclear transport of pre-ribosomes requires Noc proteins.

Bassler J, et al. (2001 Sep). Identification of a 60S preribosomal particle that is closely linked to nuclear export.

Zhang Y, et al. (2002 Jun 28). Noc3p, a bHLH protein, plays an integral role in the initiation of DNA replication in budding yeast.

Houchens CR, et al. (2008 Sep). Schizosaccharomyces pombe Noc3 is essential for ribosome biogenesis and cell division but not DNA replication.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 18 genes with posterior transmembrane prediction > 50%