FOG18030
EOG841NZV

sce:KTI11

Genes: 30

SGD Description
Zn-ribbon protein that co-purifies with Dph1 and Dph2; in a complex required for synthesis of diphthamide on translation factor eEF2 and with Elongator subunits Iki3p, Elp2p, and Elp3p; involved in modification of wobble nucleosides in tRNAs; forms a stable heterodimer with Ats1p


PomBase Description
diphthamide biosynthesis protein Dph3 (predicted)


AspGD Description
Ortholog of A. nidulans FGSC A4 : AN10254, A. fumigatus Af293 : Afu4g10530, Aspergillus wentii : Aspwe1_0047458, Aspergillus sydowii : Aspsy1_0053923 and Aspergillus terreus NIH2624 : ATET_04011


References

Fichtner L, et al. (2003 Sep). Elongator's toxin-target (TOT) function is nuclear localization sequence dependent and suppressed by post-translational modification.

Liu S, et al. (2004 Nov). Identification of the proteins required for biosynthesis of diphthamide, the target of bacterial ADP-ribosylating toxins on translation elongation factor 2.

Sun J, et al. (2005 Jun 21). Solution structure of Kti11p from Saccharomyces cerevisiae reveals a novel zinc-binding module.

Ma Y, et al. (2011). Genome-wide screening for genes associated with FK506 sensitivity in fission yeast.

Takeda K, et al. (2011). Identification of genes affecting the toxicity of anti-cancer drug bortezomib by genome-wide screening in S. pombe.

Anver S, et al. (2014 Aug). Yeast X-chromosome-associated protein 5 (Xap5) functions with H2A.Z to suppress aberrant transcripts.

Guo Y, et al. (2014 Jul). Large scale screening of genetic interaction with sgf73(+) in fission yeast.

Graml V, et al. (2014 Oct 27). A genomic Multiprocess survey of machineries that control and link cell shape, microtubule organization, and cell-cycle progression.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%