FOG17996
EOG844J5S

sce:TLG1

Genes: 27

SGD Description
Essential t-SNARE that mediates fusion of vesicles with the late Golgi; forms a complex with Tlg2p and Vti1p; mediates fusion of endosome-derived vesicles with the late Golgi; binds the docking complex VFT (Vps fifty-three) through interaction with Vps51p


PomBase Description
SNARE Tlg1 (predicted)


AspGD Description
Ortholog(s) have SNAP receptor activity, role in endocytosis, vesicle fusion and SNARE complex, cell septum, endoplasmic reticulum, endosome, trans-Golgi network localization


References

Holthuis JC, et al. (1998 Jan 2). Two syntaxin homologues in the TGN/endosomal system of yeast.

Coe JG, et al. (1999 Jul). A role for Tlg1p in the transport of proteins within the Golgi apparatus of Saccharomyces cerevisiae.

Paumet F, et al. (2001 Dec 10). A t-SNARE of the endocytic pathway must be activated for fusion.

Bock JB, et al. (2001 Feb 15). A genomic perspective on membrane compartment organization.

Siniossoglou S, et al. (2001 Nov 1). An effector of Ypt6p binds the SNARE Tlg1p and mediates selective fusion of vesicles with late Golgi membranes.

Siniossoglou S, et al. (2002 Dec 13). Vps51p links the VFT complex to the SNARE Tlg1p.

Gurunathan S, et al. (2002 May). t-SNARE phosphorylation regulates endocytosis in yeast.

Conibear E, et al. (2003 Apr). Vps51p mediates the association of the GARP (Vps52/53/54) complex with the late Golgi t-SNARE Tlg1p.

Burri L, et al. (2004 Jan). A complete set of SNAREs in yeast.

Valdez-Taubas J, et al. (2005 Jul 20). Swf1-dependent palmitoylation of the SNARE Tlg1 prevents its ubiquitination and degradation.

Starita LM, et al. (2012 Jan). Sites of ubiquitin attachment in Saccharomyces cerevisiae.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Beckley JR, et al. (2015 Dec). A Degenerate Cohort of Yeast Membrane Trafficking DUBs Mediates Cell Polarity and Survival.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 26 genes with posterior transmembrane prediction > 50%