FOG17840
EOG84J14W

sce:SBA1

Genes: 32

SGD Description
Co-chaperone that binds and regulates Hsp90 family chaperones; plays a role in determining prion variants; important for pp60v-src activity in yeast; homologous to the mammalian p23 proteins, and like p23 can regulate telomerase activity; protein abundance increases in response to DNA replication stress


PomBase Description
p23 homolog, predicted co-chaperone Wos2


AspGD Description
Putative cell cycle regulator p21 protein


References

Garrels JI, et al. (1997 Aug). Proteome studies of Saccharomyces cerevisiae: identification and characterization of abundant proteins.

Freeman BC, et al. (2000 Feb 15). The p23 molecular chaperones act at a late step in intracellular receptor action to differentially affect ligand efficacies.

Ali MM, et al. (2006 Apr 20). Crystal structure of an Hsp90-nucleotide-p23/Sba1 closed chaperone complex.

Mitochondrial localization predictions
Predotar TargetP MitoProt
Raw data
Phobius transmembrane predictions
0 genes with posterior transmembrane prediction > 50%